TY - JOUR
T1 - Nanopipette-based electrochemical SERS platforms
T2 - Using electrodeposition to produce versatile and adaptable plasmonic substrates
AU - Brasiliense, Vitor
AU - Park, Ji Eun
AU - Chen, Zhu
AU - Van Duyne, Richard P.
AU - Schatz, George C.
N1 - Funding Information:
The authors acknowledge financial support from the Air Force Office of Scientific Research, MURI grant (FA9550‐14‐1‐0003), and from the National Science Foundation, Grant CHE‐1807278. JP acknowledges support from the Assistant Secretary of Defense for Health Affairs, through the Peer Reviewed Medical Research Program under Award No. W81XWH‐16‐1‐0375. GCS acknowledges the Army Research Office, MURI grant 76578‐CH‐MUR.
Funding Information:
This work made use of the BioCryo facility of Northwestern University's NUANCE Center, which has received support from the Soft and Hybrid Nanotechnology Experimental (SHyNE) Resource (NSF ECCS‐1542205); the MRSEC program (NSF DMR‐1720139) at the Materials Research Center; the International Institute for Nanotechnology (IIN); and the State of Illinois, through the IIN. It also made use of the CryoCluster equipment, which has received support from the MRI program (NSF DMR‐1229693).
PY - 2021/2
Y1 - 2021/2
N2 - A method for fabricating localized EC-SERS probes based on nanopipettes and electrodeposition is described. Gold particles of fractal geometry with excellent SERS performance are produced, reliably and at low cost. By adapting the electrodeposition procedure, nanostructures of different sizes can be obtained, allowing the SERS platform to be tailored to many experimental configurations. In particular, by producing unique SERS platforms of dimensions comparable to the laser spot, quantitative comparison with electrochemical current is possible. By analyzing hundreds of samples, we thoroughly characterize the resulting geometry of the structures and their ability to enhance Raman signal, providing guidelines for the fabrication of optimized platforms. Control over the probes' surface potential also allows convenient modulation of surface-analyte affinity and enable chemically unstable materials, such as Cu, to be reliably used. These are demonstrated by showing that Cu particles exposed to air can be easily re-reduced, with no detriment in SERS performance.
AB - A method for fabricating localized EC-SERS probes based on nanopipettes and electrodeposition is described. Gold particles of fractal geometry with excellent SERS performance are produced, reliably and at low cost. By adapting the electrodeposition procedure, nanostructures of different sizes can be obtained, allowing the SERS platform to be tailored to many experimental configurations. In particular, by producing unique SERS platforms of dimensions comparable to the laser spot, quantitative comparison with electrochemical current is possible. By analyzing hundreds of samples, we thoroughly characterize the resulting geometry of the structures and their ability to enhance Raman signal, providing guidelines for the fabrication of optimized platforms. Control over the probes' surface potential also allows convenient modulation of surface-analyte affinity and enable chemically unstable materials, such as Cu, to be reliably used. These are demonstrated by showing that Cu particles exposed to air can be easily re-reduced, with no detriment in SERS performance.
KW - electrochemical SERS
KW - electrodeposition
KW - nanoelectrodes
KW - nanopipettes
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U2 - 10.1002/jrs.5974
DO - 10.1002/jrs.5974
M3 - Article
AN - SCOPUS:85089752074
VL - 52
SP - 339
EP - 347
JO - Journal of Raman Spectroscopy
JF - Journal of Raman Spectroscopy
SN - 0377-0486
IS - 2
ER -