Abstract
Advances in understanding enzyme catalysis have made possible development of synthetic schemes and strategies to incorporate the essential functions of enzymes into artificial structures. Two of these functions, environmental effect inherent to the active site cavity defined by the protein conformation and cooperative effect of functional groups in the cavity, have been successfully introduced into artificial structures and examined. Illustrative examples of these studies are described, as well as remaining challenges and illustrative application potentials.
| Original language | English |
|---|---|
| Pages (from-to) | 2-5 |
| Number of pages | 4 |
| Journal | Catalysis Today |
| Volume | 148 |
| Issue number | 1-2 |
| DOIs | |
| Publication status | Published - Oct 30 2010 |
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Keywords
- Active site
- Cooperative effect
- Dendrimer
- Environmental effect
- Enzyme analog
- Nanocage
- Nature-inspired
ASJC Scopus subject areas
- Catalysis
- Chemistry(all)
Cite this
Nature-inspired design and synthesis of heterogeneous and macromolecular catalysts. / Kung, Harold H; Kung, Mayfair C.
In: Catalysis Today, Vol. 148, No. 1-2, 30.10.2010, p. 2-5.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Nature-inspired design and synthesis of heterogeneous and macromolecular catalysts
AU - Kung, Harold H
AU - Kung, Mayfair C.
PY - 2010/10/30
Y1 - 2010/10/30
N2 - Advances in understanding enzyme catalysis have made possible development of synthetic schemes and strategies to incorporate the essential functions of enzymes into artificial structures. Two of these functions, environmental effect inherent to the active site cavity defined by the protein conformation and cooperative effect of functional groups in the cavity, have been successfully introduced into artificial structures and examined. Illustrative examples of these studies are described, as well as remaining challenges and illustrative application potentials.
AB - Advances in understanding enzyme catalysis have made possible development of synthetic schemes and strategies to incorporate the essential functions of enzymes into artificial structures. Two of these functions, environmental effect inherent to the active site cavity defined by the protein conformation and cooperative effect of functional groups in the cavity, have been successfully introduced into artificial structures and examined. Illustrative examples of these studies are described, as well as remaining challenges and illustrative application potentials.
KW - Active site
KW - Cooperative effect
KW - Dendrimer
KW - Environmental effect
KW - Enzyme analog
KW - Nanocage
KW - Nature-inspired
UR - http://www.scopus.com/inward/record.url?scp=74249098027&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=74249098027&partnerID=8YFLogxK
U2 - 10.1016/j.cattod.2009.02.037
DO - 10.1016/j.cattod.2009.02.037
M3 - Article
VL - 148
SP - 2
EP - 5
JO - Catalysis Today
JF - Catalysis Today
SN - 0920-5861
IS - 1-2
ER -