Nature-inspired design and synthesis of heterogeneous and macromolecular catalysts

Harold H. Kung; Mayfair C. Kung

doi:10.1016/j.cattod.2009.02.037

Nature-inspired design and synthesis of heterogeneous and macromolecular catalysts

Harold H. Kung, Mayfair C. Kung

Northwestern University

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

Advances in understanding enzyme catalysis have made possible development of synthetic schemes and strategies to incorporate the essential functions of enzymes into artificial structures. Two of these functions, environmental effect inherent to the active site cavity defined by the protein conformation and cooperative effect of functional groups in the cavity, have been successfully introduced into artificial structures and examined. Illustrative examples of these studies are described, as well as remaining challenges and illustrative application potentials.

Original language	English
Pages (from-to)	2-5
Number of pages	4
Journal	Catalysis Today
Volume	148
Issue number	1-2
DOIs	https://doi.org/10.1016/j.cattod.2009.02.037
Publication status	Published - Oct 30 2010

Keywords

Active site
Cooperative effect
Dendrimer
Environmental effect
Enzyme analog
Nanocage
Nature-inspired

ASJC Scopus subject areas

Catalysis
Chemistry(all)

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title = "Nature-inspired design and synthesis of heterogeneous and macromolecular catalysts",

abstract = "Advances in understanding enzyme catalysis have made possible development of synthetic schemes and strategies to incorporate the essential functions of enzymes into artificial structures. Two of these functions, environmental effect inherent to the active site cavity defined by the protein conformation and cooperative effect of functional groups in the cavity, have been successfully introduced into artificial structures and examined. Illustrative examples of these studies are described, as well as remaining challenges and illustrative application potentials.",

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