Non-blinking 'Giant' nanocrystal quantum dots

Ideal probes for real-time three-dimensional tracking

Jennifer A. Hollingsworth, James H. Werner, Han Htoon, Andrei Piryatinski, Richard D Schaller, Yagnaseni Ghosh, Allison M. Dennis, Aaron M. Keller, Benjamin Mangum, Daniel C. Hannah

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We describe the development and characterization of two novel non-blinking 'giant' nanocrystal quantum dot (g-NQD) systems and their application to single-particle tracking in live cells real-time and in three dimensions. The two g-NQDs - CdSe/CdS and InP/CdS - are characterized by a thick shell layer (>10 monolayers of CdS), a quasi-type-II or type-II electronic structure, and extremely suppressed non-radiative Auger recombination and photobleaching, in addition to suppressed blinking. We show that these unique traits make this new class of NQD ideal molecular probes for observing spatio-temporal dynamics of cellular processes.

Original languageEnglish
Title of host publication2013 Conference on Lasers and Electro-Optics, CLEO 2013
PublisherIEEE Computer Society
ISBN (Print)9781557529725
Publication statusPublished - 2013
Event2013 Conference on Lasers and Electro-Optics, CLEO 2013 - San Jose, CA, United States
Duration: Jun 9 2013Jun 14 2013

Other

Other2013 Conference on Lasers and Electro-Optics, CLEO 2013
CountryUnited States
CitySan Jose, CA
Period6/9/136/14/13

Fingerprint

Molecular Probes
Photobleaching
Nanocrystals
Semiconductor quantum dots
Electronic structure
Monolayers

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials

Cite this

Hollingsworth, J. A., Werner, J. H., Htoon, H., Piryatinski, A., Schaller, R. D., Ghosh, Y., ... Hannah, D. C. (2013). Non-blinking 'Giant' nanocrystal quantum dots: Ideal probes for real-time three-dimensional tracking. In 2013 Conference on Lasers and Electro-Optics, CLEO 2013 [6834475] IEEE Computer Society.

Non-blinking 'Giant' nanocrystal quantum dots : Ideal probes for real-time three-dimensional tracking. / Hollingsworth, Jennifer A.; Werner, James H.; Htoon, Han; Piryatinski, Andrei; Schaller, Richard D; Ghosh, Yagnaseni; Dennis, Allison M.; Keller, Aaron M.; Mangum, Benjamin; Hannah, Daniel C.

2013 Conference on Lasers and Electro-Optics, CLEO 2013. IEEE Computer Society, 2013. 6834475.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Hollingsworth, JA, Werner, JH, Htoon, H, Piryatinski, A, Schaller, RD, Ghosh, Y, Dennis, AM, Keller, AM, Mangum, B & Hannah, DC 2013, Non-blinking 'Giant' nanocrystal quantum dots: Ideal probes for real-time three-dimensional tracking. in 2013 Conference on Lasers and Electro-Optics, CLEO 2013., 6834475, IEEE Computer Society, 2013 Conference on Lasers and Electro-Optics, CLEO 2013, San Jose, CA, United States, 6/9/13.
Hollingsworth JA, Werner JH, Htoon H, Piryatinski A, Schaller RD, Ghosh Y et al. Non-blinking 'Giant' nanocrystal quantum dots: Ideal probes for real-time three-dimensional tracking. In 2013 Conference on Lasers and Electro-Optics, CLEO 2013. IEEE Computer Society. 2013. 6834475
Hollingsworth, Jennifer A. ; Werner, James H. ; Htoon, Han ; Piryatinski, Andrei ; Schaller, Richard D ; Ghosh, Yagnaseni ; Dennis, Allison M. ; Keller, Aaron M. ; Mangum, Benjamin ; Hannah, Daniel C. / Non-blinking 'Giant' nanocrystal quantum dots : Ideal probes for real-time three-dimensional tracking. 2013 Conference on Lasers and Electro-Optics, CLEO 2013. IEEE Computer Society, 2013.
@inproceedings{869bf252d67f4e6cb3d064da884c83ff,
title = "Non-blinking 'Giant' nanocrystal quantum dots: Ideal probes for real-time three-dimensional tracking",
abstract = "We describe the development and characterization of two novel non-blinking 'giant' nanocrystal quantum dot (g-NQD) systems and their application to single-particle tracking in live cells real-time and in three dimensions. The two g-NQDs - CdSe/CdS and InP/CdS - are characterized by a thick shell layer (>10 monolayers of CdS), a quasi-type-II or type-II electronic structure, and extremely suppressed non-radiative Auger recombination and photobleaching, in addition to suppressed blinking. We show that these unique traits make this new class of NQD ideal molecular probes for observing spatio-temporal dynamics of cellular processes.",
author = "Hollingsworth, {Jennifer A.} and Werner, {James H.} and Han Htoon and Andrei Piryatinski and Schaller, {Richard D} and Yagnaseni Ghosh and Dennis, {Allison M.} and Keller, {Aaron M.} and Benjamin Mangum and Hannah, {Daniel C.}",
year = "2013",
language = "English",
isbn = "9781557529725",
booktitle = "2013 Conference on Lasers and Electro-Optics, CLEO 2013",
publisher = "IEEE Computer Society",

}

TY - GEN

T1 - Non-blinking 'Giant' nanocrystal quantum dots

T2 - Ideal probes for real-time three-dimensional tracking

AU - Hollingsworth, Jennifer A.

AU - Werner, James H.

AU - Htoon, Han

AU - Piryatinski, Andrei

AU - Schaller, Richard D

AU - Ghosh, Yagnaseni

AU - Dennis, Allison M.

AU - Keller, Aaron M.

AU - Mangum, Benjamin

AU - Hannah, Daniel C.

PY - 2013

Y1 - 2013

N2 - We describe the development and characterization of two novel non-blinking 'giant' nanocrystal quantum dot (g-NQD) systems and their application to single-particle tracking in live cells real-time and in three dimensions. The two g-NQDs - CdSe/CdS and InP/CdS - are characterized by a thick shell layer (>10 monolayers of CdS), a quasi-type-II or type-II electronic structure, and extremely suppressed non-radiative Auger recombination and photobleaching, in addition to suppressed blinking. We show that these unique traits make this new class of NQD ideal molecular probes for observing spatio-temporal dynamics of cellular processes.

AB - We describe the development and characterization of two novel non-blinking 'giant' nanocrystal quantum dot (g-NQD) systems and their application to single-particle tracking in live cells real-time and in three dimensions. The two g-NQDs - CdSe/CdS and InP/CdS - are characterized by a thick shell layer (>10 monolayers of CdS), a quasi-type-II or type-II electronic structure, and extremely suppressed non-radiative Auger recombination and photobleaching, in addition to suppressed blinking. We show that these unique traits make this new class of NQD ideal molecular probes for observing spatio-temporal dynamics of cellular processes.

UR - http://www.scopus.com/inward/record.url?scp=84903776455&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84903776455&partnerID=8YFLogxK

M3 - Conference contribution

SN - 9781557529725

BT - 2013 Conference on Lasers and Electro-Optics, CLEO 2013

PB - IEEE Computer Society

ER -