Abstract
We describe the development and characterization of two novel non-blinking 'giant' nanocrystal quantum dot (g-NQD) systems and their application to single-particle tracking in live cells real-time and in three dimensions. The two g-NQDs - CdSe/CdS and InP/CdS - are characterized by a thick shell layer (>10 monolayers of CdS), a quasi-type-II or type-II electronic structure, and extremely suppressed non-radiative Auger recombination and photobleaching, in addition to suppressed blinking. We show that these unique traits make this new class of NQD ideal molecular probes for observing spatio-temporal dynamics of cellular processes.
| Original language | English |
|---|---|
| Title of host publication | 2013 Conference on Lasers and Electro-Optics, CLEO 2013 |
| Publisher | IEEE Computer Society |
| ISBN (Print) | 9781557529725 |
| Publication status | Published - 2013 |
| Event | 2013 Conference on Lasers and Electro-Optics, CLEO 2013 - San Jose, CA, United States Duration: Jun 9 2013 → Jun 14 2013 |
Other
| Other | 2013 Conference on Lasers and Electro-Optics, CLEO 2013 |
|---|---|
| Country | United States |
| City | San Jose, CA |
| Period | 6/9/13 → 6/14/13 |
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ASJC Scopus subject areas
- Electronic, Optical and Magnetic Materials
Cite this
Non-blinking 'Giant' nanocrystal quantum dots : Ideal probes for real-time three-dimensional tracking. / Hollingsworth, Jennifer A.; Werner, James H.; Htoon, Han; Piryatinski, Andrei; Schaller, Richard D; Ghosh, Yagnaseni; Dennis, Allison M.; Keller, Aaron M.; Mangum, Benjamin; Hannah, Daniel C.
2013 Conference on Lasers and Electro-Optics, CLEO 2013. IEEE Computer Society, 2013. 6834475.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
}
TY - GEN
T1 - Non-blinking 'Giant' nanocrystal quantum dots
T2 - Ideal probes for real-time three-dimensional tracking
AU - Hollingsworth, Jennifer A.
AU - Werner, James H.
AU - Htoon, Han
AU - Piryatinski, Andrei
AU - Schaller, Richard D
AU - Ghosh, Yagnaseni
AU - Dennis, Allison M.
AU - Keller, Aaron M.
AU - Mangum, Benjamin
AU - Hannah, Daniel C.
PY - 2013
Y1 - 2013
N2 - We describe the development and characterization of two novel non-blinking 'giant' nanocrystal quantum dot (g-NQD) systems and their application to single-particle tracking in live cells real-time and in three dimensions. The two g-NQDs - CdSe/CdS and InP/CdS - are characterized by a thick shell layer (>10 monolayers of CdS), a quasi-type-II or type-II electronic structure, and extremely suppressed non-radiative Auger recombination and photobleaching, in addition to suppressed blinking. We show that these unique traits make this new class of NQD ideal molecular probes for observing spatio-temporal dynamics of cellular processes.
AB - We describe the development and characterization of two novel non-blinking 'giant' nanocrystal quantum dot (g-NQD) systems and their application to single-particle tracking in live cells real-time and in three dimensions. The two g-NQDs - CdSe/CdS and InP/CdS - are characterized by a thick shell layer (>10 monolayers of CdS), a quasi-type-II or type-II electronic structure, and extremely suppressed non-radiative Auger recombination and photobleaching, in addition to suppressed blinking. We show that these unique traits make this new class of NQD ideal molecular probes for observing spatio-temporal dynamics of cellular processes.
UR - http://www.scopus.com/inward/record.url?scp=84903776455&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84903776455&partnerID=8YFLogxK
M3 - Conference contribution
AN - SCOPUS:84903776455
SN - 9781557529725
BT - 2013 Conference on Lasers and Electro-Optics, CLEO 2013
PB - IEEE Computer Society
ER -