Nonlinear chemical imaging nanomicroscopy: From second and third harmonic generation to multiplex (broad-bandwidth) sum frequency generation near-field scanning optical microscopy

Richard D. Schaller, Justin C. Johnson, Kevin R. Wilson, Lynn F. Lee, Louis H. Haber, Richard J. Saykally

Research output: Contribution to journalArticle

66 Citations (Scopus)


The emerging field of coherent nonlinear near-field scanning optical microscopy (NSOM) is reviewed. Second harmonic, third harmonic, and sum frequency generation (SHG, THG, and SFG) are explored as means of providing chemically and environmentally selective probes with nanometer spatial resolution provided by scanning probe microscopy. Chemical selectivity is generated via resonant enhancement of the nonlinear signals, whereas interface vs bulk contrast is achieved by the order (even vs odd) of the optical process. A method of producing higher spectral resolution, and thus increased chemical selectivity, is also demonstrated in the form of near-field detected multiplex (or "broad-bandwidth") SFG (MSFG). Applications to biological and material samples are described.

Original languageEnglish
Pages (from-to)5143-5154
Number of pages12
JournalJournal of Physical Chemistry B
Issue number20
Publication statusPublished - May 23 2002


ASJC Scopus subject areas

  • Physical and Theoretical Chemistry
  • Surfaces, Coatings and Films
  • Materials Chemistry

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