Nucleation and growth of ordered arrays of silver nanoparticles on peptide nanofibers

Hybrid nanostructures with antimicrobial properties

Elena Pazos, Eduard Sleep, Charles M Rubert Pérez, Sungsoo S. Lee, Faifan Tantakitti, Samuel I Stupp

Research output: Contribution to journalArticle

51 Citations (Scopus)

Abstract

Silver nanoparticles have been of great interest as plasmonic substrates for sensing and imaging, catalysts, or antimicrobial systems. Their physical properties are strongly dependent on parameters that remain challenging to control such as size, chemical composition, and spatial distribution. We report here on supramolecular assemblies of a novel peptide amphiphile containing aldehyde functionality in order to reduce silver ions and subsequently nucleate silver metal nanoparticles in water. This system spontaneously generates monodisperse silver particles at fairly regular distances along the length of the filamentous organic assemblies. The metal-organic hybrid structures exhibited antimicrobial activity and significantly less toxicity toward eukaryotic cells. Metallized organic nanofibers of the type described here offer the possibility to create hydrogels, which integrate the useful functions of silver nanoparticles with controllable metallic content.

Original languageEnglish
Pages (from-to)5507-5510
Number of pages4
JournalJournal of the American Chemical Society
Volume138
Issue number17
DOIs
Publication statusPublished - May 4 2016

Fingerprint

Nanofibers
Nanostructures
Silver
Nanoparticles
Peptides
Nucleation
Growth
Metal Nanoparticles
Amphiphiles
Hydrogels
Metal nanoparticles
Eukaryotic Cells
Aldehydes
Spatial distribution
Toxicity
Physical properties
Metals
Ions
Imaging techniques
Catalysts

ASJC Scopus subject areas

  • Chemistry(all)
  • Catalysis
  • Biochemistry
  • Colloid and Surface Chemistry

Cite this

Nucleation and growth of ordered arrays of silver nanoparticles on peptide nanofibers : Hybrid nanostructures with antimicrobial properties. / Pazos, Elena; Sleep, Eduard; Pérez, Charles M Rubert; Lee, Sungsoo S.; Tantakitti, Faifan; Stupp, Samuel I.

In: Journal of the American Chemical Society, Vol. 138, No. 17, 04.05.2016, p. 5507-5510.

Research output: Contribution to journalArticle

Pazos, Elena ; Sleep, Eduard ; Pérez, Charles M Rubert ; Lee, Sungsoo S. ; Tantakitti, Faifan ; Stupp, Samuel I. / Nucleation and growth of ordered arrays of silver nanoparticles on peptide nanofibers : Hybrid nanostructures with antimicrobial properties. In: Journal of the American Chemical Society. 2016 ; Vol. 138, No. 17. pp. 5507-5510.
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