One-step multilevel microfabrication by reaction-diffusion

Christopher J. Campbell, Rafal Klajn, Marcin Fialkowski, Bartosz A. Grzybowski

Research output: Contribution to journalArticle

42 Citations (Scopus)

Abstract

A new experimental technique is described that uses reaction-diffusion phenomena as a means of one-step microfabrication of complex, multilevel surface reliefs. Thin films of dry gelatin doped with potassium hexacyanoferrate are chemically micropatterned with a solution of silver nitrate delivered from an agarose stamp. Precipitation reaction between the two salts causes the surface to deform. The mechanism of surface deformation is shown to involve a sequence of reactions, diffusion, and gel swelling/contraction. This mechanism is established experimentally and provides a basis of a theoretical lattice-gas model that allows prediction surface topographies emerging from arbitrary geometries of the stamped features. The usefulness of the technique is demonstrated by using it to rapidly prepare two types of mold for passive microfluidic mixers.

Original languageEnglish
Pages (from-to)418-423
Number of pages6
JournalLangmuir
Volume21
Issue number1
DOIs
Publication statusPublished - Jan 4 2005

Fingerprint

Microfabrication
Silver Nitrate
Surface topography
Gelatin
Microfluidics
Sepharose
silver nitrates
Swelling
Potassium
Nitrates
gelatins
Silver
Gels
Salts
Gases
swelling
contraction
emerging
Thin films
potassium

ASJC Scopus subject areas

  • Physical and Theoretical Chemistry
  • Colloid and Surface Chemistry

Cite this

Campbell, C. J., Klajn, R., Fialkowski, M., & Grzybowski, B. A. (2005). One-step multilevel microfabrication by reaction-diffusion. Langmuir, 21(1), 418-423. https://doi.org/10.1021/la0487747

One-step multilevel microfabrication by reaction-diffusion. / Campbell, Christopher J.; Klajn, Rafal; Fialkowski, Marcin; Grzybowski, Bartosz A.

In: Langmuir, Vol. 21, No. 1, 04.01.2005, p. 418-423.

Research output: Contribution to journalArticle

Campbell, CJ, Klajn, R, Fialkowski, M & Grzybowski, BA 2005, 'One-step multilevel microfabrication by reaction-diffusion', Langmuir, vol. 21, no. 1, pp. 418-423. https://doi.org/10.1021/la0487747
Campbell CJ, Klajn R, Fialkowski M, Grzybowski BA. One-step multilevel microfabrication by reaction-diffusion. Langmuir. 2005 Jan 4;21(1):418-423. https://doi.org/10.1021/la0487747
Campbell, Christopher J. ; Klajn, Rafal ; Fialkowski, Marcin ; Grzybowski, Bartosz A. / One-step multilevel microfabrication by reaction-diffusion. In: Langmuir. 2005 ; Vol. 21, No. 1. pp. 418-423.
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