In this investigation, synthetic and fabrication approaches to new organic, inorganic, and hybrid materials/devices for flexible/transparent electronic applications are presented. The covered topics are: 1. Utilization of new solution-processable dielectrics exhibiting ultra-high capacitance, low leakage, and high breakdown fields. 2. Development of new low-temperature and/or solution phase processes for thin-film deposition of optically transparent inorganic/hybrid semiconductors. 3. Rational design, realization, and understanding of new electrically-active high-mobility transparent n-type organic semiconductors. We demonstrate that the combinations of these materials sets allow the fabrication of transistors and electronic circuits excellent performance characteristics. In particular, we show several examples where transparent/flexible transistors and circuits are achieved exhibiting excellent performance.