TY - JOUR
T1 - Patterned two-photon illumination by spatiotemporal shaping of ultrashort pulses
AU - Papagiakoumou, Eirini
AU - De Sars, Vincent
AU - Oron, Dan
AU - Emiliani, Valentina
N1 - Copyright:
Copyright 2018 Elsevier B.V., All rights reserved.
PY - 2008/12/22
Y1 - 2008/12/22
N2 - Multiphoton excitation by temporally focused pulses can be combined with spatial Fourier-transform pulse shaping techniques to enhance spatial control of the excitation volume. Here we propose and demonstrate an optical system for the generation of such spatiotemporally engineered light pulses using a combination of spatial control by a two-dimensional reconfigurable light modulator, with a dispersive optical setup for temporal focusing. We show that although the properties of a holographic beam significantly differ from those of plane-wave illumination used in previous temporal focusing realizations, this leads only to a slightly reduced axial resolution. We show that the system can provide scanning-less, arbitrarily shaped, depth resolved excitation patterns that offer new perspectives for multiphoton photoactivation and optical lithography applications.
AB - Multiphoton excitation by temporally focused pulses can be combined with spatial Fourier-transform pulse shaping techniques to enhance spatial control of the excitation volume. Here we propose and demonstrate an optical system for the generation of such spatiotemporally engineered light pulses using a combination of spatial control by a two-dimensional reconfigurable light modulator, with a dispersive optical setup for temporal focusing. We show that although the properties of a holographic beam significantly differ from those of plane-wave illumination used in previous temporal focusing realizations, this leads only to a slightly reduced axial resolution. We show that the system can provide scanning-less, arbitrarily shaped, depth resolved excitation patterns that offer new perspectives for multiphoton photoactivation and optical lithography applications.
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U2 - 10.1364/OE.16.022039
DO - 10.1364/OE.16.022039
M3 - Article
C2 - 19104638
AN - SCOPUS:58149117807
VL - 16
SP - 22039
EP - 22047
JO - Optics Express
JF - Optics Express
SN - 1094-4087
IS - 26
ER -