A polypyridylruthenium complex with an NAD+/NADH model ligand, [Ru(bpy)2(pbn)]2+ [bpy = 2,2'-bipyridine; pbn = 2-(2-pyridyl)-benzo[b]-1,5-naphthyridine] in a D2O/CH 3CN/triethylamine solution, undergoes stereospecific hydrogenation to give Δ-(S)-and Λ-(R)-[Ru(bpy)2(pbnDD)]2+ [pbnDD = 5,10-dideutero-2-(2-pyridyl)benzo-[b]-1,5-naphthyridine] upon visible-light irradiation. This result clearly indicates the pathway via the Π-stacked dimer of the deuterated oneelectron-reduced species. The reduction of [Ru(bpy)2(pbn)]2+ with Na2S 2O4 in D2O did not afford any stereospecific products. Furthermore, the more sterically crowded Ru complex, [Ru(dmb) 2(pbn)]2+ (dmb = 6,6'-dimethyl-2,2'-bipyridine), did not produce the corresponding pbnDD species upon irradiation.
ASJC Scopus subject areas
- Physical and Theoretical Chemistry
- Inorganic Chemistry