Extremely facile metal insertion into strong chemical bonds that are normally inert can take place in pincer systems, resulting in unequivocal demonstration and mechanistic evaluation of metal insertion into unstrained C-C and C-O bonds in a solution. This chapter presents an overview of intramolecular C-C and C-O bond activation in pincer systems. C-H and O-H bond activation processes that occur concurrently with C-C and C-O cleavages in most of the studied pincer complexes are discussed in the chapter. PCX-metal systems prove to be excellent models for strong bond activation studies. They provide mechanistic insight into the activation of strong C-C bonds. In most PCX-metal systems, C-C oxidative addition is thermodynamically more favorable than other competing C-H activation processes. C-C activation can proceed directly and does not require prior C-H activation.
ASJC Scopus subject areas
- Chemical Engineering(all)