Postsynthetic Incorporation of a Singlet Oxygen Photosensitizer in a Metal–Organic Framework for Fast and Selective Oxidative Detoxification of Sulfur Mustard

Ashlee J. Howarth, Cassandra T. Buru, Yangyang Liu, Ann M. Ploskonka, Karel J. Hartlieb, Monica McEntee, John J. Mahle, James H. Buchanan, Erin M. Durke, Salih S. Al-Juaid, J. Fraser Stoddart, Jared B. DeCoste, Joseph T Hupp, Omar K. Farha

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

A fullerene-based photosensitizer is incorporated postsynthetically into a Zr6-based MOF, NU-1000, for enhanced singlet oxygen production. The structural organic linkers in the MOF platform also act as photosensitizers which contribute to the overall generation of singlet oxygen from the material under UV irradiation. The singlet oxygen generated by the MOF/fullerene material is shown to oxidize sulfur mustard selectively to the less toxic bis(2-chloroethyl)sulfoxide with a half-life of only 11 min.

Original languageEnglish
Pages (from-to)214-218
Number of pages5
JournalChemistry - A European Journal
Volume23
Issue number1
DOIs
Publication statusPublished - Jan 1 2017

Fingerprint

Mustard Gas
Detoxification
Singlet Oxygen
Photosensitizing Agents
Photosensitizers
Fullerenes
sulfoxide
Sulfur
Oxygen
Poisons
Irradiation

Keywords

  • fullerene
  • metal–organic frameworks
  • pyrene
  • singlet oxygen
  • sulfur mustard

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Postsynthetic Incorporation of a Singlet Oxygen Photosensitizer in a Metal–Organic Framework for Fast and Selective Oxidative Detoxification of Sulfur Mustard. / Howarth, Ashlee J.; Buru, Cassandra T.; Liu, Yangyang; Ploskonka, Ann M.; Hartlieb, Karel J.; McEntee, Monica; Mahle, John J.; Buchanan, James H.; Durke, Erin M.; Al-Juaid, Salih S.; Stoddart, J. Fraser; DeCoste, Jared B.; Hupp, Joseph T; Farha, Omar K.

In: Chemistry - A European Journal, Vol. 23, No. 1, 01.01.2017, p. 214-218.

Research output: Contribution to journalArticle

Howarth, AJ, Buru, CT, Liu, Y, Ploskonka, AM, Hartlieb, KJ, McEntee, M, Mahle, JJ, Buchanan, JH, Durke, EM, Al-Juaid, SS, Stoddart, JF, DeCoste, JB, Hupp, JT & Farha, OK 2017, 'Postsynthetic Incorporation of a Singlet Oxygen Photosensitizer in a Metal–Organic Framework for Fast and Selective Oxidative Detoxification of Sulfur Mustard', Chemistry - A European Journal, vol. 23, no. 1, pp. 214-218. https://doi.org/10.1002/chem.201604972
Howarth, Ashlee J. ; Buru, Cassandra T. ; Liu, Yangyang ; Ploskonka, Ann M. ; Hartlieb, Karel J. ; McEntee, Monica ; Mahle, John J. ; Buchanan, James H. ; Durke, Erin M. ; Al-Juaid, Salih S. ; Stoddart, J. Fraser ; DeCoste, Jared B. ; Hupp, Joseph T ; Farha, Omar K. / Postsynthetic Incorporation of a Singlet Oxygen Photosensitizer in a Metal–Organic Framework for Fast and Selective Oxidative Detoxification of Sulfur Mustard. In: Chemistry - A European Journal. 2017 ; Vol. 23, No. 1. pp. 214-218.
@article{ad35f94c68cf4b1c8846cc26d73bf8c0,
title = "Postsynthetic Incorporation of a Singlet Oxygen Photosensitizer in a Metal–Organic Framework for Fast and Selective Oxidative Detoxification of Sulfur Mustard",
abstract = "A fullerene-based photosensitizer is incorporated postsynthetically into a Zr6-based MOF, NU-1000, for enhanced singlet oxygen production. The structural organic linkers in the MOF platform also act as photosensitizers which contribute to the overall generation of singlet oxygen from the material under UV irradiation. The singlet oxygen generated by the MOF/fullerene material is shown to oxidize sulfur mustard selectively to the less toxic bis(2-chloroethyl)sulfoxide with a half-life of only 11 min.",
keywords = "fullerene, metal–organic frameworks, pyrene, singlet oxygen, sulfur mustard",
author = "Howarth, {Ashlee J.} and Buru, {Cassandra T.} and Yangyang Liu and Ploskonka, {Ann M.} and Hartlieb, {Karel J.} and Monica McEntee and Mahle, {John J.} and Buchanan, {James H.} and Durke, {Erin M.} and Al-Juaid, {Salih S.} and Stoddart, {J. Fraser} and DeCoste, {Jared B.} and Hupp, {Joseph T} and Farha, {Omar K.}",
year = "2017",
month = "1",
day = "1",
doi = "10.1002/chem.201604972",
language = "English",
volume = "23",
pages = "214--218",
journal = "Chemistry - A European Journal",
issn = "0947-6539",
publisher = "Wiley-VCH Verlag",
number = "1",

}

TY - JOUR

T1 - Postsynthetic Incorporation of a Singlet Oxygen Photosensitizer in a Metal–Organic Framework for Fast and Selective Oxidative Detoxification of Sulfur Mustard

AU - Howarth, Ashlee J.

AU - Buru, Cassandra T.

AU - Liu, Yangyang

AU - Ploskonka, Ann M.

AU - Hartlieb, Karel J.

AU - McEntee, Monica

AU - Mahle, John J.

AU - Buchanan, James H.

AU - Durke, Erin M.

AU - Al-Juaid, Salih S.

AU - Stoddart, J. Fraser

AU - DeCoste, Jared B.

AU - Hupp, Joseph T

AU - Farha, Omar K.

PY - 2017/1/1

Y1 - 2017/1/1

N2 - A fullerene-based photosensitizer is incorporated postsynthetically into a Zr6-based MOF, NU-1000, for enhanced singlet oxygen production. The structural organic linkers in the MOF platform also act as photosensitizers which contribute to the overall generation of singlet oxygen from the material under UV irradiation. The singlet oxygen generated by the MOF/fullerene material is shown to oxidize sulfur mustard selectively to the less toxic bis(2-chloroethyl)sulfoxide with a half-life of only 11 min.

AB - A fullerene-based photosensitizer is incorporated postsynthetically into a Zr6-based MOF, NU-1000, for enhanced singlet oxygen production. The structural organic linkers in the MOF platform also act as photosensitizers which contribute to the overall generation of singlet oxygen from the material under UV irradiation. The singlet oxygen generated by the MOF/fullerene material is shown to oxidize sulfur mustard selectively to the less toxic bis(2-chloroethyl)sulfoxide with a half-life of only 11 min.

KW - fullerene

KW - metal–organic frameworks

KW - pyrene

KW - singlet oxygen

KW - sulfur mustard

UR - http://www.scopus.com/inward/record.url?scp=85006063449&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85006063449&partnerID=8YFLogxK

U2 - 10.1002/chem.201604972

DO - 10.1002/chem.201604972

M3 - Article

VL - 23

SP - 214

EP - 218

JO - Chemistry - A European Journal

JF - Chemistry - A European Journal

SN - 0947-6539

IS - 1

ER -