Probing the nature of charge transfer at nano-bio interfaces

Peptides on metal oxide nanoparticles

Pilarisetty Tarakeshwar, Julio L. Palma, Gregory P. Holland, Petra Fromme, Jeffery L. Yarger, Vladimiro Mujica

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Characterizing the nano-bio interface has been a long-standing endeavor in the quest for novel biosensors, biophotovoltaics, and biocompatible electronic devices. In this context, the present computational work on the interaction of two peptides, A6K (Ac-AAAAAAK-NH2) and A7 (Ac-AAAAAAA-NH2) with semiconducting TiO2 nanoparticles is an effort to understand the peptide-metal oxide nanointerface. These investigations were spurred by recent experimental observations that nanostructured semiconducting metal oxides templated with A6K peptides not only stabilize large proteins like photosystem-I (PS-I) but also exhibit enhanced charge-transfer characteristics. Our results indicate that α-helical structures of A6K are not only energetically more stabilized on TiO2 nanoparticles, but the resulting hybrids also exhibit enhanced electron transfer characteristics. This enhancement can be attributed to substantial changes in the electronic characteristics at the peptide-TiO2 interface. Apart from understanding the mechanism of electron transfer (ET) in peptide-stabilized PS-I on metal oxide nanoparticles, the current work also has implications in the development of novel solar cells and photocatalysts.

Original languageEnglish
Pages (from-to)3555-3559
Number of pages5
JournalJournal of Physical Chemistry Letters
Volume5
Issue number20
DOIs
Publication statusPublished - Oct 16 2014

Fingerprint

Oxides
Peptides
peptides
metal oxides
Photosystem I Protein Complex
Charge transfer
Metals
charge transfer
Nanoparticles
nanoparticles
Electrons
Photocatalysts
electron transfer
Biosensors
Solar cells
bioinstrumentation
electronics
solar cells
Proteins
proteins

Keywords

  • biophotovoltaics
  • charge-transfer
  • devices
  • DFT calculations
  • semiconducting nanomaterials
  • sensors

ASJC Scopus subject areas

  • Materials Science(all)

Cite this

Probing the nature of charge transfer at nano-bio interfaces : Peptides on metal oxide nanoparticles. / Tarakeshwar, Pilarisetty; Palma, Julio L.; Holland, Gregory P.; Fromme, Petra; Yarger, Jeffery L.; Mujica, Vladimiro.

In: Journal of Physical Chemistry Letters, Vol. 5, No. 20, 16.10.2014, p. 3555-3559.

Research output: Contribution to journalArticle

Tarakeshwar, Pilarisetty ; Palma, Julio L. ; Holland, Gregory P. ; Fromme, Petra ; Yarger, Jeffery L. ; Mujica, Vladimiro. / Probing the nature of charge transfer at nano-bio interfaces : Peptides on metal oxide nanoparticles. In: Journal of Physical Chemistry Letters. 2014 ; Vol. 5, No. 20. pp. 3555-3559.
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