Programmable DMA self-assemblies for nanoscale organization of ligands and proteins

Sung Ha Park, Peng Yin, Yan Liu, John H. Reif, Thomas H. Labean, Hao Yan

Research output: Contribution to journalArticle

234 Citations (Scopus)

Abstract

We demonstrate the precise control of periodic spacing between individual protein molecules by programming the self-assembly of DNA tile templates. In particular, we report the application of two self-assembled periodic DNA structures, two-dimendional nanogrids, and one-dimensional nanotrack, as template for programmable self-assembly of streptavidin protein arrays with controlled density.

Original languageEnglish
Pages (from-to)729-733
Number of pages5
JournalNano letters
Volume5
Issue number4
DOIs
Publication statusPublished - Apr 1 2005

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ASJC Scopus subject areas

  • Bioengineering
  • Chemistry(all)
  • Materials Science(all)
  • Condensed Matter Physics
  • Mechanical Engineering

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