Programmable DMA self-assemblies for nanoscale organization of ligands and proteins

Sung Ha Park, Peng Yin, Yan Liu, John H. Reif, Thomas H. Labean, Hao Yan

Research output: Contribution to journalArticle

223 Citations (Scopus)

Abstract

We demonstrate the precise control of periodic spacing between individual protein molecules by programming the self-assembly of DNA tile templates. In particular, we report the application of two self-assembled periodic DNA structures, two-dimendional nanogrids, and one-dimensional nanotrack, as template for programmable self-assembly of streptavidin protein arrays with controlled density.

Original languageEnglish
Pages (from-to)729-733
Number of pages5
JournalNano Letters
Volume5
Issue number4
DOIs
Publication statusPublished - Apr 2005

Fingerprint

Dynamic mechanical analysis
Self assembly
self assembly
DNA
templates
deoxyribonucleic acid
Ligands
proteins
Proteins
ligands
Streptavidin
tiles
Tile
programming
spacing
Molecules
molecules

ASJC Scopus subject areas

  • Materials Science(all)
  • Electronic, Optical and Magnetic Materials
  • Chemistry (miscellaneous)

Cite this

Programmable DMA self-assemblies for nanoscale organization of ligands and proteins. / Park, Sung Ha; Yin, Peng; Liu, Yan; Reif, John H.; Labean, Thomas H.; Yan, Hao.

In: Nano Letters, Vol. 5, No. 4, 04.2005, p. 729-733.

Research output: Contribution to journalArticle

Park, Sung Ha ; Yin, Peng ; Liu, Yan ; Reif, John H. ; Labean, Thomas H. ; Yan, Hao. / Programmable DMA self-assemblies for nanoscale organization of ligands and proteins. In: Nano Letters. 2005 ; Vol. 5, No. 4. pp. 729-733.
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