Protein-Functionalized Indium-Tin Oxide Nanoantenna Arrays for Selective Infrared Biosensing

Kai Chen, Peijun Guo, Thang Duy Dao, Shi Qiang Li, Satoshi Ishiii, Tadaaki Nagao, Robert P. H. Chang

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Plasmonic nanoantennas afford significantly enhanced near-fields that can be exploited for ultrasensitive molecular sensing in plasmon-enhanced vibrational spectroscopy. While elemental gold is usually used in plasmonic biosensing due to its stability and well-established surface functionalization, compound plasmonic materials with versatile surface functionalization, low-cost, and lower optical loss especially in the infrared range are receiving considerable attention. This study demonstrates the application of protein-functionalized single-crystalline indium-tin oxide (ITO) nanorod arrays for biosensing in infrared spectroscopy. The ITO nanorod arrays show angle-dependent plasmon resonances in the mid-infrared range, whose position and intensity can be readily tuned by varying the incident angle, thereby providing an easy means for selective enhancement of targeted molecular vibrations. The use of phosphonic-acid-derived biotin molecules is examined to chemically functionalize the antennas, and the specific adsorption of streptavidin onto them is subsequently demonstrated. The successful surface functionalization of the ITO nanorods demonstrated here facilitates the detection of functional biomolecules and proteins with high specificity.

Original languageEnglish
JournalAdvanced Optical Materials
DOIs
Publication statusAccepted/In press - 2017

Fingerprint

Tin oxides
Nanorods
indium oxides
Indium
tin oxides
nanorods
Infrared radiation
proteins
Proteins
Molecular vibrations
Vibrational spectroscopy
Optical losses
biotin
Streptavidin
Biomolecules
Biotin
Gold
Infrared spectroscopy
near fields
antennas

Keywords

  • Biosensing
  • Indium-tin oxide
  • Infrared spectroscopy
  • Nanoantenna
  • Surface functionalization

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics

Cite this

Protein-Functionalized Indium-Tin Oxide Nanoantenna Arrays for Selective Infrared Biosensing. / Chen, Kai; Guo, Peijun; Dao, Thang Duy; Li, Shi Qiang; Ishiii, Satoshi; Nagao, Tadaaki; Chang, Robert P. H.

In: Advanced Optical Materials, 2017.

Research output: Contribution to journalArticle

Chen, Kai ; Guo, Peijun ; Dao, Thang Duy ; Li, Shi Qiang ; Ishiii, Satoshi ; Nagao, Tadaaki ; Chang, Robert P. H. / Protein-Functionalized Indium-Tin Oxide Nanoantenna Arrays for Selective Infrared Biosensing. In: Advanced Optical Materials. 2017.
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AU - Ishiii, Satoshi

AU - Nagao, Tadaaki

AU - Chang, Robert P. H.

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