Proton-coupled electron transfer from tyrosine: A strong rate dependence on intramolecular proton transfer distance

Ming Tian Zhang, Tania Irebo, Olof Johansson, Leif Hammarström

Research output: Contribution to journalArticle

87 Citations (Scopus)

Abstract

Proton-coupled electron transfer (PCET) was examined in a series of biomimetic, covalently linked Ru II(bpy) 3-tyrosine complexes where the phenolic proton was H-bonded to an internal base (a benzimidazyl or pyridyl group). Photooxidation in laser flash/quench experiments generated the Ru III species, which triggered long-range electron transfer from the tyrosine group concerted with short-range proton transfer to the base. The results give an experimental demonstration of the strong dependence of the rate constant and kinetic isotope effect for this intramolecular PCET reaction on the effective proton transfer distance, as reflected by the experimentally determined proton donor-acceptor distance.

Original languageEnglish
Pages (from-to)13224-13227
Number of pages4
JournalJournal of the American Chemical Society
Volume133
Issue number34
DOIs
Publication statusPublished - Aug 31 2011

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)
  • Biochemistry
  • Colloid and Surface Chemistry

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