Abstract
Using a peptide amphiphile having a bulky photolabile 2-nitrobenzyl group between the alkyl chain and the peptide segment, we demonstrated quadruple helical fiber formation and its dissociation into single fibrils in response to light. Putting the bulky group close to the core of a fibril is thought to induce a distortion of the alignment of molecules, which can in turn lead to quadruple helices. Photoirradiation to cleave the bulky group transforms the helices into single fibrils.
| Original language | English |
|---|---|
| Pages (from-to) | 2946-2947 |
| Number of pages | 2 |
| Journal | Journal of the American Chemical Society |
| Volume | 130 |
| Issue number | 10 |
| DOIs | |
| Publication status | Published - Mar 12 2008 |
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ASJC Scopus subject areas
- Chemistry(all)
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Quadruple helix formation of a photoresponsive peptide amphiphile and its light-triggered dissociation into single fibers. / Muraoka, Takahiro; Cui, Honggang; Stupp, Samuel I.
In: Journal of the American Chemical Society, Vol. 130, No. 10, 12.03.2008, p. 2946-2947.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Quadruple helix formation of a photoresponsive peptide amphiphile and its light-triggered dissociation into single fibers
AU - Muraoka, Takahiro
AU - Cui, Honggang
AU - Stupp, Samuel I
PY - 2008/3/12
Y1 - 2008/3/12
N2 - Using a peptide amphiphile having a bulky photolabile 2-nitrobenzyl group between the alkyl chain and the peptide segment, we demonstrated quadruple helical fiber formation and its dissociation into single fibrils in response to light. Putting the bulky group close to the core of a fibril is thought to induce a distortion of the alignment of molecules, which can in turn lead to quadruple helices. Photoirradiation to cleave the bulky group transforms the helices into single fibrils.
AB - Using a peptide amphiphile having a bulky photolabile 2-nitrobenzyl group between the alkyl chain and the peptide segment, we demonstrated quadruple helical fiber formation and its dissociation into single fibrils in response to light. Putting the bulky group close to the core of a fibril is thought to induce a distortion of the alignment of molecules, which can in turn lead to quadruple helices. Photoirradiation to cleave the bulky group transforms the helices into single fibrils.
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UR - http://www.scopus.com/inward/citedby.url?scp=41449095163&partnerID=8YFLogxK
U2 - 10.1021/ja711213s
DO - 10.1021/ja711213s
M3 - Article
VL - 130
SP - 2946
EP - 2947
JO - Journal of the American Chemical Society
JF - Journal of the American Chemical Society
SN - 0002-7863
IS - 10
ER -