Ruthenium pincer-catalyzed acylation of alcohols using esters with liberation of hydrogen under neutral conditions

Boopathy Gnanaprakasam; Yehoshoa Ben-David; David Milstein

doi:10.1002/adsc.201000663

Ruthenium pincer-catalyzed acylation of alcohols using esters with liberation of hydrogen under neutral conditions

Boopathy Gnanaprakasam, Yehoshoa Ben-David, David Milstein

Weizmann Institute of Science, Israel

Research output: Contribution to journal › Article › peer-review

65 Citations (Scopus)

Abstract

Acylation of secondary alcohols using non-activated esters, in particular symmetrical esters (such as ethyl acetate), is achieved under neutral conditions with the liberation of molecular hydrogen. This unprecedented, environmentally benign reaction is homogenously catalyzed by a dearomatized ruthenium pincer PNN complex.

Original language	English
Pages (from-to)	3169-3173
Number of pages	5
Journal	Advanced Synthesis and Catalysis
Volume	352
Issue number	18
DOIs	https://doi.org/10.1002/adsc.201000663
Publication status	Published - Dec 17 2010

Keywords

acylation
dehydrogenation
homogeneous catalysis
ruthenium pincer complex
transesterification

ASJC Scopus subject areas

Catalysis
Organic Chemistry

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AU - Milstein, David

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KW - homogeneous catalysis

KW - ruthenium pincer complex

KW - transesterification

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