Ruthenium pincer-catalyzed acylation of alcohols using esters with liberation of hydrogen under neutral conditions

Boopathy Gnanaprakasam, Yehoshoa Ben-David, David Milstein

Research output: Contribution to journalArticle

58 Citations (Scopus)

Abstract

Acylation of secondary alcohols using non-activated esters, in particular symmetrical esters (such as ethyl acetate), is achieved under neutral conditions with the liberation of molecular hydrogen. This unprecedented, environmentally benign reaction is homogenously catalyzed by a dearomatized ruthenium pincer PNN complex.

Original languageEnglish
Pages (from-to)3169-3173
Number of pages5
JournalAdvanced Synthesis and Catalysis
Volume352
Issue number18
DOIs
Publication statusPublished - Dec 17 2010

Fingerprint

Acylation
Ruthenium
Hydrogen
Esters
Alcohols
ethyl acetate

Keywords

  • acylation
  • dehydrogenation
  • homogeneous catalysis
  • ruthenium pincer complex
  • transesterification

ASJC Scopus subject areas

  • Catalysis
  • Organic Chemistry

Cite this

Ruthenium pincer-catalyzed acylation of alcohols using esters with liberation of hydrogen under neutral conditions. / Gnanaprakasam, Boopathy; Ben-David, Yehoshoa; Milstein, David.

In: Advanced Synthesis and Catalysis, Vol. 352, No. 18, 17.12.2010, p. 3169-3173.

Research output: Contribution to journalArticle

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