Scaffolded DNA origami of a DNA tetrahedron molecular container

Yonggang Ke, Jaswinder Sharma, Minghui Liu, Kasper Jahn, Yan Liu, Hao Yan

Research output: Contribution to journalArticle

202 Citations (Scopus)

Abstract

We describe a strategy of scaffolded DNA origami to design and construct 3D molecular cages of tetrahedron geometry with inside volume closed by triangular faces. Each edge of the triangular face is ∼54 nm in dimension. The estimated total external volume and the internal cavity of the triangular pyramid are about 1.8 × 10 -23 and 1.5 × 10 -23 m 3, respectively. Correct formation of the tetrahedron DNA cage was verified by gel electrophoresis, atomic force microscopy, transmission electron microscopy, and dynamic light scattering techniques.

Original languageEnglish
Pages (from-to)2445-2447
Number of pages3
JournalNano Letters
Volume9
Issue number6
DOIs
Publication statusPublished - Jun 10 2009

Fingerprint

containers
tetrahedrons
Containers
DNA
deoxyribonucleic acid
Dynamic light scattering
electrophoresis
pyramids
Electrophoresis
Atomic force microscopy
light scattering
Gels
atomic force microscopy
gels
Transmission electron microscopy
transmission electron microscopy
cavities
Geometry
geometry

ASJC Scopus subject areas

  • Condensed Matter Physics
  • Bioengineering
  • Chemistry(all)
  • Materials Science(all)
  • Mechanical Engineering

Cite this

Scaffolded DNA origami of a DNA tetrahedron molecular container. / Ke, Yonggang; Sharma, Jaswinder; Liu, Minghui; Jahn, Kasper; Liu, Yan; Yan, Hao.

In: Nano Letters, Vol. 9, No. 6, 10.06.2009, p. 2445-2447.

Research output: Contribution to journalArticle

Ke, Yonggang ; Sharma, Jaswinder ; Liu, Minghui ; Jahn, Kasper ; Liu, Yan ; Yan, Hao. / Scaffolded DNA origami of a DNA tetrahedron molecular container. In: Nano Letters. 2009 ; Vol. 9, No. 6. pp. 2445-2447.
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