TY - JOUR
T1 - Scalable synthesis and post-modification of a mesoporous metal-organic framework called NU-1000
AU - Wang, Timothy C.
AU - Vermeulen, Nicolaas A.
AU - Kim, In Soo
AU - Martinson, Alex B.F.
AU - Fraser Stoddart, J.
AU - Hupp, Joseph T.
AU - Farha, Omar K.
N1 - Funding Information:
acknowleDGMents This work (MOF assembly, experimental characterization and AIM) was supported as part of the Inorganometallic Catalyst Design Center, an Energy Frontier Research Center, funded by the US Department of Energy, Office of Science, Basic Energy Sciences, under Award no. DESC0012702 (to O.K.F., A.B.F.M. and J.T.H.). This research is part (project 34-944) of the Joint Center of Excellence in Integrated Nano-Systems (JCIN) at King Abdulaziz City for Science and Technology (KACST) and Northwestern University (NU; to J.F.S.). The authors thank both KACST and NU for their continued support of this research.
Publisher Copyright:
© 2015 Nature America, Inc. All rights reserved.
Copyright:
Copyright 2017 Elsevier B.V., All rights reserved.
PY - 2016/1/3
Y1 - 2016/1/3
N2 - The synthesis of NU-1000, a highly robust mesoporous (containing pores >2 nm) metal-organic framework (MOF), can be conducted efficiently on a multigram scale from inexpensive starting materials. Tetrabromopyrene and (4-(ethoxycarbonyl)phenyl)boronic acid can easily be coupled to prepare the requisite organic strut with four metal-binding sites in the form of four carboxylic acids, while zirconyl chloride octahydrate is used as a precursor for the well-defined metal oxide clusters. NU-1000 has been reported as an excellent candidate for the separation of gases, and it is a versatile scaffold for heterogeneous catalysis. In particular, it is ideal for the catalytic deactivation of nerve agents, and it shows great promise as a new generic platform for a wide range of applications. Multiple post-synthetic modification protocols have been developed using NU-1000 as the parent material, making it a potentially useful scaffold for several catalytic applications. The procedure for the preparation of NU-1000 can be scaled up reliably, and it is suitable for the production of 50 g of the tetracarboxylic acid containing organic linker and 200 mg-2.5 g of NU-1000. The entire synthesis is performed without purification by column chromatography and can be completed within 10 d.
AB - The synthesis of NU-1000, a highly robust mesoporous (containing pores >2 nm) metal-organic framework (MOF), can be conducted efficiently on a multigram scale from inexpensive starting materials. Tetrabromopyrene and (4-(ethoxycarbonyl)phenyl)boronic acid can easily be coupled to prepare the requisite organic strut with four metal-binding sites in the form of four carboxylic acids, while zirconyl chloride octahydrate is used as a precursor for the well-defined metal oxide clusters. NU-1000 has been reported as an excellent candidate for the separation of gases, and it is a versatile scaffold for heterogeneous catalysis. In particular, it is ideal for the catalytic deactivation of nerve agents, and it shows great promise as a new generic platform for a wide range of applications. Multiple post-synthetic modification protocols have been developed using NU-1000 as the parent material, making it a potentially useful scaffold for several catalytic applications. The procedure for the preparation of NU-1000 can be scaled up reliably, and it is suitable for the production of 50 g of the tetracarboxylic acid containing organic linker and 200 mg-2.5 g of NU-1000. The entire synthesis is performed without purification by column chromatography and can be completed within 10 d.
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U2 - 10.1038/nprot.2016.001
DO - 10.1038/nprot.2016.001
M3 - Article
C2 - 26678084
AN - SCOPUS:84979865078
VL - 11
SP - 149
EP - 162
JO - Nature Protocols
JF - Nature Protocols
SN - 1754-2189
IS - 1
ER -