Selective hydrogenation of nitriles to primary amines catalyzed by a novel iron complex

Subrata Chakraborty, Gregory Leitus, David Milstein

Research output: Contribution to journalArticle

48 Citations (Scopus)

Abstract

Hydrogenation of nitriles to primary amines constitutes an atom-efficient and environmentally benign synthetic reaction. Herein we present a novel complex based on earth-abundant iron, and its application in the catalytic homogeneous hydrogenation of (hetero)aromatic, benzylic, and aliphatic nitriles to selectively form primary amines.

Original languageEnglish
Pages (from-to)1812-1815
Number of pages4
JournalChemical Communications
Volume52
Issue number9
DOIs
Publication statusPublished - Dec 3 2015

Fingerprint

Nitriles
Hydrogenation
Amines
Iron
Earth (planet)
Atoms

ASJC Scopus subject areas

  • Chemistry(all)
  • Catalysis
  • Ceramics and Composites
  • Electronic, Optical and Magnetic Materials
  • Surfaces, Coatings and Films
  • Materials Chemistry
  • Metals and Alloys

Cite this

Selective hydrogenation of nitriles to primary amines catalyzed by a novel iron complex. / Chakraborty, Subrata; Leitus, Gregory; Milstein, David.

In: Chemical Communications, Vol. 52, No. 9, 03.12.2015, p. 1812-1815.

Research output: Contribution to journalArticle

Chakraborty, Subrata ; Leitus, Gregory ; Milstein, David. / Selective hydrogenation of nitriles to primary amines catalyzed by a novel iron complex. In: Chemical Communications. 2015 ; Vol. 52, No. 9. pp. 1812-1815.
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