Selective hydrogenation of nitriles to primary amines catalyzed by a novel iron complex

Subrata Chakraborty, Gregory Leitus, David Milstein

Research output: Contribution to journalArticle

63 Citations (Scopus)


Hydrogenation of nitriles to primary amines constitutes an atom-efficient and environmentally benign synthetic reaction. Herein we present a novel complex based on earth-abundant iron, and its application in the catalytic homogeneous hydrogenation of (hetero)aromatic, benzylic, and aliphatic nitriles to selectively form primary amines.

Original languageEnglish
Pages (from-to)1812-1815
Number of pages4
JournalChemical Communications
Issue number9
Publication statusPublished - Dec 3 2015


ASJC Scopus subject areas

  • Chemistry(all)
  • Catalysis
  • Ceramics and Composites
  • Electronic, Optical and Magnetic Materials
  • Surfaces, Coatings and Films
  • Materials Chemistry
  • Metals and Alloys

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