Selective N-Formylation of Amines with H2 and CO2 Catalyzed by Cobalt Pincer Complexes

Prosenjit Daw, Subrata Chakraborty, Gregory Leitus, Yael Diskin-Posner, Yehoshoa Ben-David, David Milstein

Research output: Contribution to journal › Article

62 Citations (Scopus)

Abstract

N-formylation of amines utilizing CO2 in the presence of reducing agents constitute an important methodology in organic synthesis. Presented herein is a selective N-formylation of amines with CO2 and H2 catalyzed by complexes of Earth-abundant cobalt. A wide range of amines were converted to their corresponding formamides under CO2 and H2 pressure, catalyzed by Co-PNP pincer complex, generating water as the sole byproduct.

Original languageEnglish
Pages (from-to)2500-2504
Number of pages5
JournalACS Catalysis
Volume7
Issue number4
DOIs
Publication statusPublished - Apr 7 2017

Fingerprint

Cobalt
Amines
Formamides
Reducing Agents
Reducing agents
Byproducts
Earth (planet)
Water

Keywords

  • CO
  • cobalt
  • formylation
  • hydrogenation
  • pincer

ASJC Scopus subject areas

  • Catalysis

Cite this

Selective N-Formylation of Amines with H2 and CO2 Catalyzed by Cobalt Pincer Complexes. / Daw, Prosenjit; Chakraborty, Subrata; Leitus, Gregory; Diskin-Posner, Yael; Ben-David, Yehoshoa; Milstein, David.

In: ACS Catalysis, Vol. 7, No. 4, 07.04.2017, p. 2500-2504.

Research output: Contribution to journal › Article

Daw, P, Chakraborty, S, Leitus, G, Diskin-Posner, Y, Ben-David, Y & Milstein, D 2017, 'Selective N-Formylation of Amines with H2 and CO2 Catalyzed by Cobalt Pincer Complexes', ACS Catalysis, vol. 7, no. 4, pp. 2500-2504. https://doi.org/10.1021/acscatal.7b00116
Daw P, Chakraborty S, Leitus G, Diskin-Posner Y, Ben-David Y, Milstein D. Selective N-Formylation of Amines with H2 and CO2 Catalyzed by Cobalt Pincer Complexes. ACS Catalysis. 2017 Apr 7;7(4):2500-2504. https://doi.org/10.1021/acscatal.7b00116
Daw, Prosenjit ; Chakraborty, Subrata ; Leitus, Gregory ; Diskin-Posner, Yael ; Ben-David, Yehoshoa ; Milstein, David. / Selective N-Formylation of Amines with H2 and CO2 Catalyzed by Cobalt Pincer Complexes. In: ACS Catalysis. 2017 ; Vol. 7, No. 4. pp. 2500-2504.
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