Selective synthesis of primary amines directly from alcohols and ammonia

Chidambaram Gunanathan, David Milstein

Research output: Contribution to journalArticle

334 Citations (Scopus)

Abstract

(Chemical Equation Presented) Air stable and waterproof: Selective and efficient synthesis of primary amines directly from alcohols and ammonia is achieved under mild conditions (see scheme). The reaction is homogenously catalyzed by a novel air-stable ruthenium pincer complex and can proceed in toluene or even in the absence of solvent or "on water".

Original languageEnglish
Pages (from-to)8661-8664
Number of pages4
JournalAngewandte Chemie - International Edition
Volume47
Issue number45
DOIs
Publication statusPublished - Oct 27 2008

Fingerprint

Ammonia
Amines
Alcohols
Ruthenium
Toluene
Air
Water

Keywords

  • Amines
  • Homogeneous catalysis
  • Pincer ligands
  • Ruthenium
  • Synthetic methods

ASJC Scopus subject areas

  • Chemistry(all)
  • Catalysis

Cite this

Selective synthesis of primary amines directly from alcohols and ammonia. / Gunanathan, Chidambaram; Milstein, David.

In: Angewandte Chemie - International Edition, Vol. 47, No. 45, 27.10.2008, p. 8661-8664.

Research output: Contribution to journalArticle

@article{2061813995064b7c9306d02bc4ec224b,
title = "Selective synthesis of primary amines directly from alcohols and ammonia",
abstract = "(Chemical Equation Presented) Air stable and waterproof: Selective and efficient synthesis of primary amines directly from alcohols and ammonia is achieved under mild conditions (see scheme). The reaction is homogenously catalyzed by a novel air-stable ruthenium pincer complex and can proceed in toluene or even in the absence of solvent or {"}on water{"}.",
keywords = "Amines, Homogeneous catalysis, Pincer ligands, Ruthenium, Synthetic methods",
author = "Chidambaram Gunanathan and David Milstein",
year = "2008",
month = "10",
day = "27",
doi = "10.1002/anie.200803229",
language = "English",
volume = "47",
pages = "8661--8664",
journal = "Angewandte Chemie - International Edition",
issn = "1433-7851",
publisher = "John Wiley and Sons Ltd",
number = "45",

}

TY - JOUR

T1 - Selective synthesis of primary amines directly from alcohols and ammonia

AU - Gunanathan, Chidambaram

AU - Milstein, David

PY - 2008/10/27

Y1 - 2008/10/27

N2 - (Chemical Equation Presented) Air stable and waterproof: Selective and efficient synthesis of primary amines directly from alcohols and ammonia is achieved under mild conditions (see scheme). The reaction is homogenously catalyzed by a novel air-stable ruthenium pincer complex and can proceed in toluene or even in the absence of solvent or "on water".

AB - (Chemical Equation Presented) Air stable and waterproof: Selective and efficient synthesis of primary amines directly from alcohols and ammonia is achieved under mild conditions (see scheme). The reaction is homogenously catalyzed by a novel air-stable ruthenium pincer complex and can proceed in toluene or even in the absence of solvent or "on water".

KW - Amines

KW - Homogeneous catalysis

KW - Pincer ligands

KW - Ruthenium

KW - Synthetic methods

UR - http://www.scopus.com/inward/record.url?scp=55249090662&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=55249090662&partnerID=8YFLogxK

U2 - 10.1002/anie.200803229

DO - 10.1002/anie.200803229

M3 - Article

C2 - 18846519

AN - SCOPUS:55249090662

VL - 47

SP - 8661

EP - 8664

JO - Angewandte Chemie - International Edition

JF - Angewandte Chemie - International Edition

SN - 1433-7851

IS - 45

ER -