Self-assembled peptide nanoarrays

An approach to studying protein-protein interactions

Berea A R Williams, Kyle Lund, Yan Liu, Hao Yan, John C. Chaput

Research output: Contribution to journalArticle

96 Citations (Scopus)

Abstract

(Figure Presented) On show: High-density peptide arrays capable of displaying many different amino acid sequences at well-defined and addressable locations on the same DNA nanostructure have been produced. The strategy used relies on the genetic information encoded in the nucleic acid portion of a DNA-tagged peptide to position the amino acid sequence at a predetermined location on the array.

Original languageEnglish
Pages (from-to)3051-3054
Number of pages4
JournalAngewandte Chemie - International Edition
Volume46
Issue number17
DOIs
Publication statusPublished - 2007

Fingerprint

Peptides
Amino acids
DNA
Proteins
Amino Acids
Nucleic acids
Nucleic Acids
Nanostructures

Keywords

  • DNA
  • Nanostructures
  • Peptide nanoarrays
  • Self-assembly

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Self-assembled peptide nanoarrays : An approach to studying protein-protein interactions. / Williams, Berea A R; Lund, Kyle; Liu, Yan; Yan, Hao; Chaput, John C.

In: Angewandte Chemie - International Edition, Vol. 46, No. 17, 2007, p. 3051-3054.

Research output: Contribution to journalArticle

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