Separation of stabilized MOPS gold nanostars by density gradient centrifugation

Kavita Chandra, Vished Kumar, Stephanie E. Werner, Teri W Odom

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

This article describes the stabilization and postsynthetic separation of gold nanostars (AuNS) synthesized with a morpholine-based Good's buffer, 3-(N-morpholino)propanesulfonic acid. Resuspension of AuNS in ultrapure water improved the shape stability of the particles over 30 days. We demonstrated the sorting of nanostars via rate-zonal centrifugation through a linear sucrose gradient based on branch length and number. We determined that one round of centrifugation was sufficient for separation. Also, we improved the structural homogeneity and stability of the nanoparticles through the optimization of the storage conditions and established a robust method to sort AuNS based on size and shape.

Original languageEnglish
Pages (from-to)4878-4884
Number of pages7
JournalACS Omega
Volume2
Issue number8
DOIs
Publication statusPublished - Jan 1 2017

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Centrifugation
Gold
Morpholinos
Sugar (sucrose)
Sorting
Sucrose
Buffers
Stabilization
Nanoparticles
Acids
Water
morpholinopropane sulfonic acid
morpholine

ASJC Scopus subject areas

  • Chemistry(all)
  • Chemical Engineering(all)

Cite this

Separation of stabilized MOPS gold nanostars by density gradient centrifugation. / Chandra, Kavita; Kumar, Vished; Werner, Stephanie E.; Odom, Teri W.

In: ACS Omega, Vol. 2, No. 8, 01.01.2017, p. 4878-4884.

Research output: Contribution to journalArticle

Chandra, Kavita ; Kumar, Vished ; Werner, Stephanie E. ; Odom, Teri W. / Separation of stabilized MOPS gold nanostars by density gradient centrifugation. In: ACS Omega. 2017 ; Vol. 2, No. 8. pp. 4878-4884.
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