Abstract
Surface-enhanced Raman scattering (SERS) has been historically considered a tool for physical scientists. Recently, however, a new avenue has opened for the application of SERS in the medical field, mainly spurred by the implementation of SERS tags. SERS tags are employed for the indirect identification of target molecules, similarly to what fluorescent dyes do, but with several intrinsic advantages. They have proven very useful in in vivo, ex vivo, and in vitro identification of cancerous cells and tissues, with targeting selectivity that can be tuned to recognize individual markers. It has also been demonstrated for the first time that surgical outcomes may be improved via the use of SERS tags, leading to complete tumor resection. Herein, I will explain how SERS tags can aid in the identification of cancerous tissues at the single cell level and how they promise to render SERS a powerful tool for personalized cancer detection.
| Original language | English |
|---|---|
| Pages (from-to) | 249-258 |
| Number of pages | 10 |
| Journal | ChemNanoMat |
| Volume | 2 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - Jan 1 2016 |
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Keywords
- cancer
- molecular imaging
- plasmonic nanoparticles
- SERS tags
- surface-enhanced Raman scattering
ASJC Scopus subject areas
- Biomaterials
- Renewable Energy, Sustainability and the Environment
- Energy Engineering and Power Technology
- Materials Chemistry
Cite this
SERS Tags : The Next Promising Tool for Personalized Cancer Detection? / Fabris, Laura.
In: ChemNanoMat, Vol. 2, No. 4, 01.01.2016, p. 249-258.Research output: Contribution to journal › Review article
}
TY - JOUR
T1 - SERS Tags
T2 - The Next Promising Tool for Personalized Cancer Detection?
AU - Fabris, Laura
PY - 2016/1/1
Y1 - 2016/1/1
N2 - Surface-enhanced Raman scattering (SERS) has been historically considered a tool for physical scientists. Recently, however, a new avenue has opened for the application of SERS in the medical field, mainly spurred by the implementation of SERS tags. SERS tags are employed for the indirect identification of target molecules, similarly to what fluorescent dyes do, but with several intrinsic advantages. They have proven very useful in in vivo, ex vivo, and in vitro identification of cancerous cells and tissues, with targeting selectivity that can be tuned to recognize individual markers. It has also been demonstrated for the first time that surgical outcomes may be improved via the use of SERS tags, leading to complete tumor resection. Herein, I will explain how SERS tags can aid in the identification of cancerous tissues at the single cell level and how they promise to render SERS a powerful tool for personalized cancer detection.
AB - Surface-enhanced Raman scattering (SERS) has been historically considered a tool for physical scientists. Recently, however, a new avenue has opened for the application of SERS in the medical field, mainly spurred by the implementation of SERS tags. SERS tags are employed for the indirect identification of target molecules, similarly to what fluorescent dyes do, but with several intrinsic advantages. They have proven very useful in in vivo, ex vivo, and in vitro identification of cancerous cells and tissues, with targeting selectivity that can be tuned to recognize individual markers. It has also been demonstrated for the first time that surgical outcomes may be improved via the use of SERS tags, leading to complete tumor resection. Herein, I will explain how SERS tags can aid in the identification of cancerous tissues at the single cell level and how they promise to render SERS a powerful tool for personalized cancer detection.
KW - cancer
KW - molecular imaging
KW - plasmonic nanoparticles
KW - SERS tags
KW - surface-enhanced Raman scattering
UR - http://www.scopus.com/inward/record.url?scp=85013053675&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85013053675&partnerID=8YFLogxK
U2 - 10.1002/cnma.201500221
DO - 10.1002/cnma.201500221
M3 - Review article
AN - SCOPUS:85013053675
VL - 2
SP - 249
EP - 258
JO - ChemNanoMat
JF - ChemNanoMat
SN - 2199-692X
IS - 4
ER -