Simple synthesis of 2-substituted tetrahydrofuran-3-carbonitriles

M. Makosza, J. Przyborowski, R. Klajn, A. Kwast

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Liquid/liquid Phase Transfer Catalysis (PTC) reaction of 4-chlorobutyronitrile with nonenolisable aldehydes leads via an addition-cyclisation reaction sequence to derivatives of tetrahydrofuran-3-carbonitrile.

Original languageEnglish
Pages (from-to)1773-1774
Number of pages2
JournalSynlett
Issue number12
Publication statusPublished - Dec 1 2000

    Fingerprint

Keywords

  • Aldehydes
  • Cyclizations
  • Nitriles
  • Phase-transfer catalysis
  • Tetrahydrofurans

ASJC Scopus subject areas

  • Organic Chemistry

Cite this

Makosza, M., Przyborowski, J., Klajn, R., & Kwast, A. (2000). Simple synthesis of 2-substituted tetrahydrofuran-3-carbonitriles. Synlett, (12), 1773-1774.