Site-specific synthesis and in situ immobilization of fluorescent silver nanoclusters on DNA nanoscaffolds by use of the tollens reaction

Suchetan Pal, Reji Varghese, Zhengtao Deng, Zhao Zhao, Ashok Kumar, Hao Yan, Yan Liu

Research output: Contribution to journalArticle

59 Citations (Scopus)


Origami embellished with silver: DNA strands with specific sequences and covalently attached sugar moieties were used for the site-specific incorporation of the sugar units on a DNA origami scaffold. This approach enabled the subsequent site-specific synthesis and in situ immobilization of fluorescent Ag clusters at predefined positions on the DNA nanoscaffold by treatment with the Tollens reagent (see picture).

Original languageEnglish
Pages (from-to)4176-4179
Number of pages4
JournalAngewandte Chemie - International Edition
Issue number18
Publication statusPublished - Apr 26 2011



  • DNA origami
  • Tollens reaction
  • fluorescence
  • self-assembly
  • silver nanoclusters

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)

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