Size control of arsenic trioxide nanocrystals grown in nanowells

Eun Ah You, Richard W. Ahn, Hyung Lee Min, Meera R. Raja, Thomas V. O'Halloran, Teri W Odom

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

(Figure Presented) This paper describes a new strategy to generate nanocrystalline drugs through the precipitation of drug molecules in attoliter nanowells. We controlled the size of arsenic trioxide (ATO) nanocrystals by simply changing the concentration of ATO solution in the nanowells; particles with sizes ranging from 55 to 175 nm were formed. This approach only requires the drugs to be soluble in a solvent and thus can be broadly applicable to produce other drugs in nanocrystalline form.

Original languageEnglish
Pages (from-to)10863-10865
Number of pages3
JournalJournal of the American Chemical Society
Volume131
Issue number31
DOIs
Publication statusPublished - Aug 12 2009

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Arsenic
Nanoparticles
Nanocrystals
Pharmaceutical Preparations
Molecules
Particle Size
arsenic trioxide

ASJC Scopus subject areas

  • Chemistry(all)
  • Catalysis
  • Biochemistry
  • Colloid and Surface Chemistry

Cite this

Size control of arsenic trioxide nanocrystals grown in nanowells. / You, Eun Ah; Ahn, Richard W.; Min, Hyung Lee; Raja, Meera R.; O'Halloran, Thomas V.; Odom, Teri W.

In: Journal of the American Chemical Society, Vol. 131, No. 31, 12.08.2009, p. 10863-10865.

Research output: Contribution to journalArticle

You, EA, Ahn, RW, Min, HL, Raja, MR, O'Halloran, TV & Odom, TW 2009, 'Size control of arsenic trioxide nanocrystals grown in nanowells', Journal of the American Chemical Society, vol. 131, no. 31, pp. 10863-10865. https://doi.org/10.1021/ja902117b
You, Eun Ah ; Ahn, Richard W. ; Min, Hyung Lee ; Raja, Meera R. ; O'Halloran, Thomas V. ; Odom, Teri W. / Size control of arsenic trioxide nanocrystals grown in nanowells. In: Journal of the American Chemical Society. 2009 ; Vol. 131, No. 31. pp. 10863-10865.
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