Size-selective incorporation of DNA nanocages into nanoporous antimony-doped tin oxide materials

Chad R. Simmons, Dominik Schmitt, Xixi Wei, Dongran Han, Alex M. Volosin, Danielle M. Ladd, Dong Kyun Seo, Yan Liu, Hao Yan

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

A conductive nanoporous antimony-doped tin oxide (ATO) powder has been prepared using the sol-gel method that contains three-dimensionally interconnected pores within the metal oxide and highly tunable pore sizes on the nanoscale. It is demonstrated that these porous materials possess the capability of hosting a tetrahedral-shaped DNA nanostructure of defined dimensions with high affinity. The tunability of pore size enables the porous substrate to selectively absorb the DNA nanostructures into the metal oxide cavities or exclude them from entering the surface layer. Both confocal fluorescence microscopy and solution FRET experiments revealed that the DNA nanostructures maintained their integrity upon the size-selective incorporation into the cavities of the porous materials. As DNA nanostructures can serve as a stable three-dimensional nanoscaffold for the coordination of electron transfer mediators, this work opens up new possibilities of incorporating functionalized DNA architectures as guest molecules to nanoporous conductive metal oxides for applications such as photovoltaics, sensors, and solar fuel cells.

Original languageEnglish
Pages (from-to)6060-6068
Number of pages9
JournalACS Nano
Volume5
Issue number7
DOIs
Publication statusPublished - Jul 26 2011

Fingerprint

Antimony
antimony
Tin oxides
tin oxides
DNA
deoxyribonucleic acid
Nanostructures
Oxides
metal oxides
Metals
porous materials
porosity
Pore size
Porous materials
cavities
Confocal microscopy
Fluorescence microscopy
Powders
integrity
Sol-gel process

Keywords

  • antimony-doped tin oxide (ATO)
  • conductive metal oxides
  • DNA nanocages
  • DNA nanotechnology
  • nanoporous materials

ASJC Scopus subject areas

  • Engineering(all)
  • Materials Science(all)
  • Physics and Astronomy(all)

Cite this

Simmons, C. R., Schmitt, D., Wei, X., Han, D., Volosin, A. M., Ladd, D. M., ... Yan, H. (2011). Size-selective incorporation of DNA nanocages into nanoporous antimony-doped tin oxide materials. ACS Nano, 5(7), 6060-6068. https://doi.org/10.1021/nn2019286

Size-selective incorporation of DNA nanocages into nanoporous antimony-doped tin oxide materials. / Simmons, Chad R.; Schmitt, Dominik; Wei, Xixi; Han, Dongran; Volosin, Alex M.; Ladd, Danielle M.; Seo, Dong Kyun; Liu, Yan; Yan, Hao.

In: ACS Nano, Vol. 5, No. 7, 26.07.2011, p. 6060-6068.

Research output: Contribution to journalArticle

Simmons CR, Schmitt D, Wei X, Han D, Volosin AM, Ladd DM et al. Size-selective incorporation of DNA nanocages into nanoporous antimony-doped tin oxide materials. ACS Nano. 2011 Jul 26;5(7):6060-6068. https://doi.org/10.1021/nn2019286
Simmons, Chad R. ; Schmitt, Dominik ; Wei, Xixi ; Han, Dongran ; Volosin, Alex M. ; Ladd, Danielle M. ; Seo, Dong Kyun ; Liu, Yan ; Yan, Hao. / Size-selective incorporation of DNA nanocages into nanoporous antimony-doped tin oxide materials. In: ACS Nano. 2011 ; Vol. 5, No. 7. pp. 6060-6068.
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