Sodium periodate mediated oxidative transformations in organic synthesis

Arumugam Sudalai, Alexander Khenkin, Ronny Neumann

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

The investigation of new oxidative transformations for the synthesis of carbon-heteroatom and heteroatom-heteroatom bonds is of fundamental importance in the synthesis of numerous bioactive molecules and fine chemicals. In this context, NaIO4, an exciting reagent, has attracted increasing attention enabling the development of these unprecedented oxidative transformations that are difficult to achieve otherwise. Thus, NaIO4 has been successfully explored as a versatile oxidant for a variety of fundamental organic transformations such as C-H activation, oxidative functionalization of alkenes and other interesting oxidative transformations and its application in the synthesis of bioactive natural products. This review summarizes recent developments in this area with NaIO4 as a versatile oxidant and brings out many challenges that still remain elusive for the future.

Original languageEnglish
Pages (from-to)4374-4394
Number of pages21
JournalOrganic and Biomolecular Chemistry
Volume13
Issue number15
DOIs
Publication statusPublished - Apr 21 2015

Fingerprint

Synthetic Chemistry Techniques
Oxidants
sodium
Alkenes
synthesis
activity (biology)
Biological Products
Carbon
Chemical activation
alkenes
reagents
Molecules
activation
metaperiodate
carbon
products
molecules

ASJC Scopus subject areas

  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Biochemistry

Cite this

Sodium periodate mediated oxidative transformations in organic synthesis. / Sudalai, Arumugam; Khenkin, Alexander; Neumann, Ronny.

In: Organic and Biomolecular Chemistry, Vol. 13, No. 15, 21.04.2015, p. 4374-4394.

Research output: Contribution to journalArticle

Sudalai, Arumugam ; Khenkin, Alexander ; Neumann, Ronny. / Sodium periodate mediated oxidative transformations in organic synthesis. In: Organic and Biomolecular Chemistry. 2015 ; Vol. 13, No. 15. pp. 4374-4394.
@article{e56caecb08e04dfa9bed5168c1fa6535,
title = "Sodium periodate mediated oxidative transformations in organic synthesis",
abstract = "The investigation of new oxidative transformations for the synthesis of carbon-heteroatom and heteroatom-heteroatom bonds is of fundamental importance in the synthesis of numerous bioactive molecules and fine chemicals. In this context, NaIO4, an exciting reagent, has attracted increasing attention enabling the development of these unprecedented oxidative transformations that are difficult to achieve otherwise. Thus, NaIO4 has been successfully explored as a versatile oxidant for a variety of fundamental organic transformations such as C-H activation, oxidative functionalization of alkenes and other interesting oxidative transformations and its application in the synthesis of bioactive natural products. This review summarizes recent developments in this area with NaIO4 as a versatile oxidant and brings out many challenges that still remain elusive for the future.",
author = "Arumugam Sudalai and Alexander Khenkin and Ronny Neumann",
year = "2015",
month = "4",
day = "21",
doi = "10.1039/c5ob00238a",
language = "English",
volume = "13",
pages = "4374--4394",
journal = "Organic and Biomolecular Chemistry",
issn = "1477-0520",
publisher = "Royal Society of Chemistry",
number = "15",

}

TY - JOUR

T1 - Sodium periodate mediated oxidative transformations in organic synthesis

AU - Sudalai, Arumugam

AU - Khenkin, Alexander

AU - Neumann, Ronny

PY - 2015/4/21

Y1 - 2015/4/21

N2 - The investigation of new oxidative transformations for the synthesis of carbon-heteroatom and heteroatom-heteroatom bonds is of fundamental importance in the synthesis of numerous bioactive molecules and fine chemicals. In this context, NaIO4, an exciting reagent, has attracted increasing attention enabling the development of these unprecedented oxidative transformations that are difficult to achieve otherwise. Thus, NaIO4 has been successfully explored as a versatile oxidant for a variety of fundamental organic transformations such as C-H activation, oxidative functionalization of alkenes and other interesting oxidative transformations and its application in the synthesis of bioactive natural products. This review summarizes recent developments in this area with NaIO4 as a versatile oxidant and brings out many challenges that still remain elusive for the future.

AB - The investigation of new oxidative transformations for the synthesis of carbon-heteroatom and heteroatom-heteroatom bonds is of fundamental importance in the synthesis of numerous bioactive molecules and fine chemicals. In this context, NaIO4, an exciting reagent, has attracted increasing attention enabling the development of these unprecedented oxidative transformations that are difficult to achieve otherwise. Thus, NaIO4 has been successfully explored as a versatile oxidant for a variety of fundamental organic transformations such as C-H activation, oxidative functionalization of alkenes and other interesting oxidative transformations and its application in the synthesis of bioactive natural products. This review summarizes recent developments in this area with NaIO4 as a versatile oxidant and brings out many challenges that still remain elusive for the future.

UR - http://www.scopus.com/inward/record.url?scp=84926330409&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84926330409&partnerID=8YFLogxK

U2 - 10.1039/c5ob00238a

DO - 10.1039/c5ob00238a

M3 - Article

AN - SCOPUS:84926330409

VL - 13

SP - 4374

EP - 4394

JO - Organic and Biomolecular Chemistry

JF - Organic and Biomolecular Chemistry

SN - 1477-0520

IS - 15

ER -