Spontaneous and X-ray-triggered crystallization at long range in self-assembling filament networks

Honggang Cui, E. Thomas Pashuck, Yuri S. Velichko, Steven J. Weigand, Andrew G. Cheetham, Christina J. Newcomb, Samuel I Stupp

Research output: Contribution to journalArticle

109 Citations (Scopus)

Abstract

We report here crystallization at long range in networks of like-charge supramolecular peptide filaments mediated by repulsive forces. The crystallization is spontaneous beyond a given concentration of the molecules that form the filaments but can be triggered by x-rays at lower concentrations. The crystalline domains formed by x-ray irradiation, with interfilament separations of up to 320 angstroms, can be stable for hours after the beam is turned off, and ions that screen charges on the filaments suppress ordering. We hypothesize that the stability of crystalline domains emerges from a balance of repulsive tensions linked to native or x-ray-induced charges and the mechanical compressive entrapment of filaments within a network. Similar phenomena may occur naturally in the cytoskeleton of cells and, if induced externally in biological or artificial systems, lead to possible biomedical and lithographic functions.

Original languageEnglish
Pages (from-to)555-559
Number of pages5
JournalScience
Volume327
Issue number5965
DOIs
Publication statusPublished - 2010

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Crystallization
X-Rays
Cytoskeleton
Ions
Peptides

ASJC Scopus subject areas

  • General

Cite this

Cui, H., Pashuck, E. T., Velichko, Y. S., Weigand, S. J., Cheetham, A. G., Newcomb, C. J., & Stupp, S. I. (2010). Spontaneous and X-ray-triggered crystallization at long range in self-assembling filament networks. Science, 327(5965), 555-559. https://doi.org/10.1126/science.1182340

Spontaneous and X-ray-triggered crystallization at long range in self-assembling filament networks. / Cui, Honggang; Pashuck, E. Thomas; Velichko, Yuri S.; Weigand, Steven J.; Cheetham, Andrew G.; Newcomb, Christina J.; Stupp, Samuel I.

In: Science, Vol. 327, No. 5965, 2010, p. 555-559.

Research output: Contribution to journalArticle

Cui, H, Pashuck, ET, Velichko, YS, Weigand, SJ, Cheetham, AG, Newcomb, CJ & Stupp, SI 2010, 'Spontaneous and X-ray-triggered crystallization at long range in self-assembling filament networks', Science, vol. 327, no. 5965, pp. 555-559. https://doi.org/10.1126/science.1182340
Cui H, Pashuck ET, Velichko YS, Weigand SJ, Cheetham AG, Newcomb CJ et al. Spontaneous and X-ray-triggered crystallization at long range in self-assembling filament networks. Science. 2010;327(5965):555-559. https://doi.org/10.1126/science.1182340
Cui, Honggang ; Pashuck, E. Thomas ; Velichko, Yuri S. ; Weigand, Steven J. ; Cheetham, Andrew G. ; Newcomb, Christina J. ; Stupp, Samuel I. / Spontaneous and X-ray-triggered crystallization at long range in self-assembling filament networks. In: Science. 2010 ; Vol. 327, No. 5965. pp. 555-559.
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