Structure of the reaction center from Rhodobacter sphaeroides R-26: the protein subunits.

James Paul Allen, G. Feher, T. O. Yeates, H. Komiya, D. C. Rees

Research output: Contribution to journalArticle

531 Citations (Scopus)

Abstract

The three-dimensional structure of the protein subunits of the reaction center (RC) of Rhodobacter sphaeroides has been determined by x-ray diffraction at a resolution of 2.8 A with an R factor of 26%. The L and M subunits each contain five transmembrane helices and several helices that do not span the membrane. The L and M subunits are related to each other by a 2-fold rotational symmetry axis that is approximately the same as that determined for the cofactors. The H subunit has one transmembrane helix and a globular domain on the cytoplasmic side, which contains a helix that does not span the membrane and several beta-sheets. The structural homology with RCs from other purple bacteria is discussed. A structure of the complex formed between the water soluble cytochrome c2 and the RC from Rb. sphaeroides is proposed.

Original languageEnglish
Pages (from-to)6162-6166
Number of pages5
JournalProceedings of the National Academy of Sciences of the United States of America
Volume84
Issue number17
Publication statusPublished - Sep 1987

ASJC Scopus subject areas

  • General
  • Genetics

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