Supramolecular polymers in aqueous media

Elisha Krieg, Maartje M C Bastings, Pol Besenius, Boris Rybtchinski

Research output: Contribution to journalReview article

273 Citations (Scopus)


This review discusses one-dimensional supramolecular polymers that form in aqueous media. First, naturally occurring supramolecular polymers are described, in particular, amyloid fibrils, actin filaments, and microtubules. Their structural, thermodynamic, kinetic, and nanomechanical properties are highlighted, as well as their importance for the advancement of biologically inspired supramolecular polymer materials. Second, five classes of synthetic supramolecular polymers are described: systems based on (1) hydrogen-bond motifs, (2) large φ-conjugated surfaces, (3) host-guest interactions, (4) peptides, and (5) DNA. We focus on recent studies that address key challenges in the field, providing mechanistic understanding, rational polymer design, important functionality, robustness, or unusual thermodynamic and kinetic properties.

Original languageEnglish
Pages (from-to)2414-2477
Number of pages64
JournalChemical Reviews
Issue number4
Publication statusPublished - Jan 4 2016


ASJC Scopus subject areas

  • Chemistry(all)

Cite this