Surface-specific functionalization of nanoscale metal-organic frameworks

Shunzhi Wang, William Morris, Yangyang Liu, C. Michael McGuirk, Yu Zhou, Joseph T Hupp, Omar K. Farha, Chad A. Mirkin

Research output: Contribution to journalArticle

59 Citations (Scopus)

Abstract

A method for modifying the external surfaces of a series of nanoscale metal-organic frameworks (MOFs) with 1,2-dioleoyl-sn-glycero-3-phosphate (DOPA) is presented. A series of zirconium-based nanoMOFs of the same topology (UiO-66, UiO-67, and BUT-30) were synthesized, isolated as aggregates, and then conjugated with DOPA to create stably dispersed colloids. BET surface area analysis revealed that these structures maintain their porosity after surface functionalization, providing evidence that DOPA functionalization only occurs on the external surface. Additionally, dye-labeled ligand loading studies revealed that the density of DOPA on the surface of the nanoscale MOF correlates to the density of metal nodes on the surface of each MOF. Importantly, the surface modification strategy described will allow for the general and divergent synthesis and study of a wide variety of nanoscale MOFs as stable colloidal materials. Zr-based MOF nanoparticles densely surface-modified with 1,2-dioleoyl-sn-glycero-3-phosphate (DOPA) showed dramatically altered colloidal properties. Post-synthetic modifications can thus be used to modify nanoMOF surface chemistry by coordination to exposed metal-containing units, while retaining crystallinity and permanent porosity.

Original languageEnglish
Pages (from-to)14738-14742
Number of pages5
JournalAngewandte Chemie - International Edition
Volume54
Issue number49
DOIs
Publication statusPublished - 2015

Fingerprint

Metals
Phosphates
Porosity
Colloids
Surface chemistry
Zirconium
Surface treatment
Coloring Agents
Dyes
Ligands
Topology
Nanoparticles
dioleoylphosphatidic acid

Keywords

  • metal-organic frameworks
  • phosphate lipids
  • post-synthetic modification
  • surface functionalization
  • zirconium oxo clusters

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)

Cite this

Surface-specific functionalization of nanoscale metal-organic frameworks. / Wang, Shunzhi; Morris, William; Liu, Yangyang; McGuirk, C. Michael; Zhou, Yu; Hupp, Joseph T; Farha, Omar K.; Mirkin, Chad A.

In: Angewandte Chemie - International Edition, Vol. 54, No. 49, 2015, p. 14738-14742.

Research output: Contribution to journalArticle

Wang, S, Morris, W, Liu, Y, McGuirk, CM, Zhou, Y, Hupp, JT, Farha, OK & Mirkin, CA 2015, 'Surface-specific functionalization of nanoscale metal-organic frameworks', Angewandte Chemie - International Edition, vol. 54, no. 49, pp. 14738-14742. https://doi.org/10.1002/anie.201506888
Wang, Shunzhi ; Morris, William ; Liu, Yangyang ; McGuirk, C. Michael ; Zhou, Yu ; Hupp, Joseph T ; Farha, Omar K. ; Mirkin, Chad A. / Surface-specific functionalization of nanoscale metal-organic frameworks. In: Angewandte Chemie - International Edition. 2015 ; Vol. 54, No. 49. pp. 14738-14742.
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