Synthesis of aromatic aldehydes by oxidative hydroxymethylation

Oiena Branytska, Ronny Neumann

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

A new high yield method for the synthesis of aromatic aldehydes has been developed. The procedure is based on an acid catalyzed hydroxymethylation of an arene substrate by paraformaldehyde with concurrent selective oxidation of the intermediate aromatic carbinol by 2,3-dichloro-5,6-dicyanobenzoquinone (DDQ) to the aldehyde product.

Original languageEnglish
Pages (from-to)1575-1576
Number of pages2
JournalSynlett
Issue number9
DOIs
Publication statusPublished - Jul 22 2004

Keywords

  • Aldehydes
  • Arenes
  • Electrophilic aromatic substitutions
  • Oxidations
  • Quinones

ASJC Scopus subject areas

  • Organic Chemistry

Fingerprint Dive into the research topics of 'Synthesis of aromatic aldehydes by oxidative hydroxymethylation'. Together they form a unique fingerprint.

Cite this