Abstract
Base-metal catalyzed dehydrogenative self-coupling of 2-amino alcohols to selectively form functionalized 2,5-substituted pyrazine derivatives is presented. Also, 2-substituted quinoxaline derivatives are synthesized by dehydrogenative coupling of 1,2-diaminobenzene and 1,2-diols. In both cases, water and hydrogen gas are formed as the sole byproducts. The reactions are catalyzed by acridine-based pincer complexes of earth-abundant manganese.
Original language | English |
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Pages (from-to) | 7734-7741 |
Number of pages | 8 |
Journal | ACS Catalysis |
Volume | 8 |
Issue number | 9 |
DOIs | |
Publication status | Published - Sep 7 2018 |
Keywords
- dehydrogenative coupling
- manganese
- pincer
- pyrazine
- quinoxaline
ASJC Scopus subject areas
- Catalysis
- Chemistry(all)