The core and most useful molecules in organic chemistry

Kyle J.M. Bishop, Rafal Klajn, Bartosz A. Grzybowski

Research output: Contribution to journalArticlepeer-review

54 Citations (Scopus)


The fruitful core: Organic syntheses reported in the literature from 1850 to 2004 are analyzed with mathematical tools from network theory and statistical physics. There is a set of substances (the core) from which the majority of other organic compounds can be made (see picture; red: core, blue: periphery, green: islands). Search algorithms are used to identify small optimal sets of maximally useful chemicals. (Figure Presented).

Original languageEnglish
Pages (from-to)5348-5354
Number of pages7
JournalAngewandte Chemie - International Edition
Issue number32
Publication statusPublished - Aug 4 2006


  • History of science
  • Network theory
  • Organic chemistry
  • Synthetic methods

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)

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