The core and most useful molecules in organic chemistry

Kyle J.M. Bishop; Rafal Klajn; Bartosz A. Grzybowski

doi:10.1002/anie.200600881

The core and most useful molecules in organic chemistry

Kyle J.M. Bishop, Rafal Klajn, Bartosz A. Grzybowski

Weizmann Institute of Science, Israel

Research output: Contribution to journal › Article › peer-review

49 Citations (Scopus)

Abstract

The fruitful core: Organic syntheses reported in the literature from 1850 to 2004 are analyzed with mathematical tools from network theory and statistical physics. There is a set of substances (the core) from which the majority of other organic compounds can be made (see picture; red: core, blue: periphery, green: islands). Search algorithms are used to identify small optimal sets of maximally useful chemicals. (Figure Presented).

Original language	English
Pages (from-to)	5348-5354
Number of pages	7
Journal	Angewandte Chemie - International Edition
Volume	45
Issue number	32
DOIs	https://doi.org/10.1002/anie.200600881
Publication status	Published - Aug 4 2006

Keywords

History of science
Network theory
Organic chemistry
Synthetic methods

ASJC Scopus subject areas

Catalysis
Chemistry(all)

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10.1002/anie.200600881

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