The product-forming step in palladium-catalysed methoxycarbonylation of organic halides

David Milstein

Research output: Contribution to journal › Article

61 Citations (Scopus)

Abstract

Use of trimethylphosphine-palladium complexes renders the product-forming step in palladium-catalysed methoxycarbonylation of benzyl chloride or iodobenzene rate-determining and allows for its direct observation; the product-forming step is alcoholysis of an acylpalladium complex and not reductive elimination of a methoxycarbonylpalladium intermediate.

Original languageEnglish
Pages (from-to)817-818
Number of pages2
JournalJournal of the Chemical Society, Chemical Communications
Issue number11
DOIs
Publication statusPublished - 1986

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Palladium
Observation
iodobenzene
benzyl chloride

ASJC Scopus subject areas

  • Molecular Medicine

Cite this

The product-forming step in palladium-catalysed methoxycarbonylation of organic halides. / Milstein, David.

In: Journal of the Chemical Society, Chemical Communications, No. 11, 1986, p. 817-818.

Research output: Contribution to journal › Article

Milstein, D 1986, 'The product-forming step in palladium-catalysed methoxycarbonylation of organic halides', Journal of the Chemical Society, Chemical Communications, no. 11, pp. 817-818. https://doi.org/10.1039/C39860000817
Milstein D. The product-forming step in palladium-catalysed methoxycarbonylation of organic halides. Journal of the Chemical Society, Chemical Communications. 1986;(11):817-818. https://doi.org/10.1039/C39860000817
Milstein, David. / The product-forming step in palladium-catalysed methoxycarbonylation of organic halides. In: Journal of the Chemical Society, Chemical Communications. 1986 ; No. 11. pp. 817-818.
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