The product-forming step in palladium-catalysed methoxycarbonylation of organic halides

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Abstract

Use of trimethylphosphine-palladium complexes renders the product-forming step in palladium-catalysed methoxycarbonylation of benzyl chloride or iodobenzene rate-determining and allows for its direct observation; the product-forming step is alcoholysis of an acylpalladium complex and not reductive elimination of a methoxycarbonylpalladium intermediate.

Original languageEnglish
Pages (from-to)817-818
Number of pages2
JournalJournal of the Chemical Society, Chemical Communications
Issue number11
DOIs
Publication statusPublished - 1986

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Palladium
Observation
iodobenzene
benzyl chloride

ASJC Scopus subject areas

  • Molecular Medicine

Cite this

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title = "The product-forming step in palladium-catalysed methoxycarbonylation of organic halides",
abstract = "Use of trimethylphosphine-palladium complexes renders the product-forming step in palladium-catalysed methoxycarbonylation of benzyl chloride or iodobenzene rate-determining and allows for its direct observation; the product-forming step is alcoholysis of an acylpalladium complex and not reductive elimination of a methoxycarbonylpalladium intermediate.",
author = "David Milstein",
year = "1986",
doi = "10.1039/C39860000817",
language = "English",
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journal = "Chemical Communications",
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