The structure of bryostatin 2 from the marine Bryozoan Bugula neritina

George R. Pettit, Cherry L. Herald, Yoshiaki Kamano, John Devens Gust, Reiko Aoyagi

Research output: Contribution to journalArticle

64 Citations (Scopus)

Abstract

The marine Bryozoan Bugula neritina L. has been found to contain a new series (17) of related macrolides remarkably active against the murine P-388 lymphocytic leukemia. Based primarily upon high resolution (400 MHz) 1H-nmr studies, the second member of the series, bryostatin 2, has been shown to be the 20-membered ring lactone 1b.

Original languageEnglish
Pages (from-to)528-531
Number of pages4
JournalJournal of Natural Products
Volume46
Issue number4
Publication statusPublished - 1983

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ASJC Scopus subject areas

  • Plant Science
  • Chemistry (miscellaneous)
  • Drug Discovery
  • Organic Chemistry
  • Pharmacology

Cite this

Pettit, G. R., Herald, C. L., Kamano, Y., Gust, J. D., & Aoyagi, R. (1983). The structure of bryostatin 2 from the marine Bryozoan Bugula neritina. Journal of Natural Products, 46(4), 528-531.