Abstract
The first example of hydrogenation of amides homogeneously catalyzed by an earth-abundant metal complex is reported. The reaction is catalyzed by iron PNP pincer complexes. A wide range of secondary and tertiary N-substituted 2,2,2-trifluoroacetamides were hydrogenated to form amines and trifluoroethanol.
| Original language | English |
|---|---|
| Pages (from-to) | 5285-5288 |
| Number of pages | 4 |
| Journal | Chemical Communications |
| Volume | 52 |
| Issue number | 30 |
| DOIs | |
| Publication status | Published - Apr 18 2016 |
ASJC Scopus subject areas
- Catalysis
- Electronic, Optical and Magnetic Materials
- Ceramics and Composites
- Chemistry(all)
- Surfaces, Coatings and Films
- Metals and Alloys
- Materials Chemistry
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Garg, J. A., Chakraborty, S., Ben-David, Y., & Milstein, D. (2016). Unprecedented iron-catalyzed selective hydrogenation of activated amides to amines and alcohols. Chemical Communications, 52(30), 5285-5288. https://doi.org/10.1039/c6cc01505k