Unprecedented iron-catalyzed selective hydrogenation of activated amides to amines and alcohols

Jai Anand Garg, Subrata Chakraborty, Yehoshoa Ben-David, David Milstein

Research output: Contribution to journalArticle

57 Citations (Scopus)

Abstract

The first example of hydrogenation of amides homogeneously catalyzed by an earth-abundant metal complex is reported. The reaction is catalyzed by iron PNP pincer complexes. A wide range of secondary and tertiary N-substituted 2,2,2-trifluoroacetamides were hydrogenated to form amines and trifluoroethanol.

Original languageEnglish
Pages (from-to)5285-5288
Number of pages4
JournalChemical Communications
Volume52
Issue number30
DOIs
Publication statusPublished - Apr 18 2016

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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